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Circulating microRNAs as potential markers of human drug-induced liver injury.
Starkey Lewis PJ, Dear J, Platt V, Simpson KJ, Craig DG, Antoine DJ, French NS, Dhaun N, Webb DJ, Costello EM, Neoptolemos JP, Moggs J, Goldring CE, Park BK. Starkey Lewis PJ, et al. Among authors: moggs j. Hepatology. 2011 Nov;54(5):1767-76. doi: 10.1002/hep.24538. Hepatology. 2011. PMID: 22045675 Clinical Trial.
Serum microRNA biomarkers for drug-induced liver injury.
Starkey Lewis PJ, Merz M, Couttet P, Grenet O, Dear J, Antoine DJ, Goldring C, Park BK, Moggs JG. Starkey Lewis PJ, et al. Among authors: moggs jg. Clin Pharmacol Ther. 2012 Sep;92(3):291-3. doi: 10.1038/clpt.2012.101. Epub 2012 Jul 25. Clin Pharmacol Ther. 2012. PMID: 22828715 Review.
Retro-orbital blood acquisition facilitates circulating microRNA measurement in zebrafish with paracetamol hepatotoxicity.
Vliegenthart AD, Starkey Lewis P, Tucker CS, Del Pozo J, Rider S, Antoine DJ, Dubost V, Westphal M, Moulin P, Bailey MA, Moggs JG, Goldring CE, Park BK, Dear JW. Vliegenthart AD, et al. Among authors: moggs jg. Zebrafish. 2014 Jun;11(3):219-26. doi: 10.1089/zeb.2013.0912. Epub 2014 Mar 13. Zebrafish. 2014. PMID: 24625211 Free PMC article.
Challenges and approaches for the development of safer immunomodulatory biologics.
Sathish JG, Sethu S, Bielsky MC, de Haan L, French NS, Govindappa K, Green J, Griffiths CE, Holgate S, Jones D, Kimber I, Moggs J, Naisbitt DJ, Pirmohamed M, Reichmann G, Sims J, Subramanyam M, Todd MD, Van Der Laan JW, Weaver RJ, Park BK. Sathish JG, et al. Among authors: moggs j. Nat Rev Drug Discov. 2013 Apr;12(4):306-24. doi: 10.1038/nrd3974. Nat Rev Drug Discov. 2013. PMID: 23535934 Free PMC article. Review.
Defining baseline epigenetic landscapes in the rat liver.
Thomson JP, Ottaviano R, Buesen R, Moggs JG, Schwarz M, Meehan RR. Thomson JP, et al. Epigenomics. 2017 Dec;9(12):1503-1527. doi: 10.2217/epi-2017-0029. Epub 2017 Nov 13. Epigenomics. 2017. PMID: 29130343 Free PMC article.
Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.
Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth RS, Webb S, Kerr AR, Lyall MJ, Drake AJ, Wolf CR, Moggs JG, Schwarz M, Meehan RR. Thomson JP, et al. Among authors: moggs jg. Cancer Res. 2016 May 15;76(10):3097-108. doi: 10.1158/0008-5472.CAN-15-1910. Epub 2016 Apr 6. Cancer Res. 2016. PMID: 27197233 Free PMC article.
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.
Lempiäinen H, Müller A, Brasa S, Teo SS, Roloff TC, Morawiec L, Zamurovic N, Vicart A, Funhoff E, Couttet P, Schübeler D, Grenet O, Marlowe J, Moggs J, Terranova R. Lempiäinen H, et al. Among authors: moggs j. PLoS One. 2011 Mar 24;6(3):e18216. doi: 10.1371/journal.pone.0018216. PLoS One. 2011. PMID: 21455306 Free PMC article.
Perturbation of microRNAs in rat heart during chronic doxorubicin treatment.
Vacchi-Suzzi C, Bauer Y, Berridge BR, Bongiovanni S, Gerrish K, Hamadeh HK, Letzkus M, Lyon J, Moggs J, Paules RS, Pognan F, Staedtler F, Vidgeon-Hart MP, Grenet O, Couttet P. Vacchi-Suzzi C, et al. Among authors: moggs j. PLoS One. 2012;7(7):e40395. doi: 10.1371/journal.pone.0040395. Epub 2012 Jul 31. PLoS One. 2012. PMID: 22859947 Free PMC article.
81 results