Gilbert IH - Search Results

1

Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.

Hampton SE, Baragaña B, Schipani A, Bosch-Navarrete C, Musso-Buendía JA, Recio E, Kaiser M, Whittingham JL, Roberts SM, Shevtsov M, Brannigan JA, Kahnberg P, Brun R, Wilson KS, González-Pacanowska D, Johansson NG, Gilbert IH. Hampton SE, et al. Among authors: gilbert ih. ChemMedChem. 2011 Oct 4;6(10):1816-31. doi: 10.1002/cmdc.201100255. ChemMedChem. 2011. PMID: 22049550

2

The structure-based design and synthesis of selective inhibitors of Trypanosoma cruzi dihydrofolate reductase.

Zuccotto F, Brun R, Gonzalez Pacanowska D, Ruiz Perez LM, Gilbert IH. Zuccotto F, et al. Among authors: gilbert ih. Bioorg Med Chem Lett. 1999 May 17;9(10):1463-8. doi: 10.1016/s0960-894x(99)00213-9. Bioorg Med Chem Lett. 1999. PMID: 10360757

3

Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase.

Chowdhury SF, Villamor VB, Guerrero RH, Leal I, Brun R, Croft SL, Goodman JM, Maes L, Ruiz-Perez LM, Pacanowska DG, Gilbert IH. Chowdhury SF, et al. Among authors: gilbert ih. J Med Chem. 1999 Oct 21;42(21):4300-12. doi: 10.1021/jm981130+. J Med Chem. 1999. PMID: 10543874

4

Novel inhibitors of Trypanosoma cruzi dihydrofolate reductase.

Zuccotto F, Zvelebil M, Brun R, Chowdhury SF, Di Lucrezia R, Leal I, Maes L, Ruiz-Perez LM, Gonzalez Pacanowska D, Gilbert IH. Zuccotto F, et al. Among authors: gilbert ih. Eur J Med Chem. 2001 May;36(5):395-405. doi: 10.1016/s0223-5234(01)01235-1. Eur J Med Chem. 2001. PMID: 11451529

5

Synthesis and biological evaluation of s-triazine substituted polyamines as potential new anti-trypanosomal drugs.

Klenke B, Stewart M, Barrett MP, Brun R, Gilbert IH. Klenke B, et al. Among authors: gilbert ih. J Med Chem. 2001 Oct 11;44(21):3440-52. doi: 10.1021/jm010854+. J Med Chem. 2001. PMID: 11585449

6

Synthesis and testing of 5-benzyl-2,4-diaminopyrimidines as potential inhibitors of leishmanial and trypanosomal dihydrofolate reductase.

Chowdhury SF, Guerrero RH, Brun R, Ruiz-Perez LM, Pacanowska DG, Gilbert IH. Chowdhury SF, et al. Among authors: gilbert ih. J Enzyme Inhib Med Chem. 2002 Oct;17(5):293-302. doi: 10.1080/1475636021000059083. J Enzyme Inhib Med Chem. 2002. PMID: 12683746 Free article.

7

Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis.

Dardonville C, Rinaldi E, Hanau S, Barrett MP, Brun R, Gilbert IH. Dardonville C, et al. Among authors: gilbert ih. Bioorg Med Chem. 2003 Jul 17;11(14):3205-14. doi: 10.1016/s0968-0896(03)00191-3. Bioorg Med Chem. 2003. PMID: 12818683

8

Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines.

Klenke B, Barrett MP, Brun R, Gilbert IH. Klenke B, et al. Among authors: gilbert ih. J Antimicrob Chemother. 2003 Aug;52(2):290-3. doi: 10.1093/jac/dkg307. Epub 2003 Jul 1. J Antimicrob Chemother. 2003. PMID: 12837742

9

2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase.

Pez D, Leal I, Zuccotto F, Boussard C, Brun R, Croft SL, Yardley V, Ruiz Perez LM, Gonzalez Pacanowska D, Gilbert IH. Pez D, et al. Among authors: gilbert ih. Bioorg Med Chem. 2003 Nov 3;11(22):4693-711. doi: 10.1016/j.bmc.2003.08.012. Bioorg Med Chem. 2003. PMID: 14556785

10

Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi.

Magaraci F, Jimenez CJ, Rodrigues C, Rodrigues JC, Braga MV, Yardley V, de Luca-Fradley K, Croft SL, de Souza W, Ruiz-Perez LM, Urbina J, Gonzalez Pacanowska D, Gilbert IH. Magaraci F, et al. Among authors: gilbert ih. J Med Chem. 2003 Oct 23;46(22):4714-27. doi: 10.1021/jm021114j. J Med Chem. 2003. PMID: 14561091

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