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Page 1
Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase.
Hampton SE, Baragaña B, Schipani A, Bosch-Navarrete C, Musso-Buendía JA, Recio E, Kaiser M, Whittingham JL, Roberts SM, Shevtsov M, Brannigan JA, Kahnberg P, Brun R, Wilson KS, González-Pacanowska D, Johansson NG, Gilbert IH. Hampton SE, et al. Among authors: johansson ng. ChemMedChem. 2011 Oct 4;6(10):1816-31. doi: 10.1002/cmdc.201100255. ChemMedChem. 2011. PMID: 22049550
Modified 5'-trityl nucleosides as inhibitors of Plasmodium falciparum dUTPase.
Ruda GF, Nguyen C, Ziemkowski P, Felczak K, Kasinathan G, Musso-Buendia A, Sund C, Zhou XX, Kaiser M, Ruiz-Pérez LM, Brun R, Kulikowski T, Johansson NG, González-Pacanowska D, Gilbert IH. Ruda GF, et al. Among authors: johansson ng. ChemMedChem. 2011 Feb 7;6(2):309-20. doi: 10.1002/cmdc.201000445. Epub 2011 Jan 18. ChemMedChem. 2011. PMID: 21246738
β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.
Baragaña B, McCarthy O, Sánchez P, Bosch-Navarrete C, Kaiser M, Brun R, Whittingham JL, Roberts SM, Zhou XX, Wilson KS, Johansson NG, González-Pacanowska D, Gilbert IH. Baragaña B, et al. Among authors: johansson ng. Bioorg Med Chem. 2011 Apr 1;19(7):2378-91. doi: 10.1016/j.bmc.2011.02.012. Epub 2011 Feb 17. Bioorg Med Chem. 2011. PMID: 21411327
Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the Plasmodium falciparum dUTPase.
Hampton SE, Schipani A, Bosch-Navarrete C, Recio E, Kaiser M, Kahnberg P, González-Pacanowska D, Johansson NG, Gilbert IH. Hampton SE, et al. Among authors: johansson ng. Bioorg Med Chem. 2013 Sep 15;21(18):5876-85. doi: 10.1016/j.bmc.2013.07.004. Epub 2013 Jul 12. Bioorg Med Chem. 2013. PMID: 23916149 Free PMC article.
Validation of Plasmodium falciparum dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity.
Pérez-Moreno G, Sánchez-Carrasco P, Ruiz-Pérez LM, Johansson NG, Müller S, Baragaña B, Hampton SE, Gilbert IH, Kaiser M, Sarkar S, Pandurangan T, Kumar V, González-Pacanowska D. Pérez-Moreno G, et al. Among authors: johansson ng. Malar J. 2019 Dec 3;18(1):392. doi: 10.1186/s12936-019-3025-2. Malar J. 2019. PMID: 31796083 Free PMC article.
dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors.
Whittingham JL, Leal I, Nguyen C, Kasinathan G, Bell E, Jones AF, Berry C, Benito A, Turkenburg JP, Dodson EJ, Ruiz Perez LM, Wilkinson AJ, Johansson NG, Brun R, Gilbert IH, Gonzalez Pacanowska D, Wilson KS. Whittingham JL, et al. Among authors: johansson ng. Structure. 2005 Feb;13(2):329-38. doi: 10.1016/j.str.2004.11.015. Structure. 2005. PMID: 15698576 Free article.
Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase.
Nguyen C, Ruda GF, Schipani A, Kasinathan G, Leal I, Musso-Buendia A, Kaiser M, Brun R, Ruiz-Pérez LM, Sahlberg BL, Johansson NG, Gonzalez-Pacanowska D, Gilbert IH. Nguyen C, et al. Among authors: johansson ng. J Med Chem. 2006 Jul 13;49(14):4183-95. doi: 10.1021/jm060126s. J Med Chem. 2006. PMID: 16821778
Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni.
Musso-Buendía JA, Vidal AE, Kasinthan G, Nguyen C, Carrero-Lérida J, Ruiz-Pérez LM, Wilson K, Johansson NG, Gilbert IH, González-Pacanowska D. Musso-Buendía JA, et al. Among authors: johansson ng. J Enzyme Inhib Med Chem. 2009 Feb;24(1):111-6. doi: 10.1080/14756360801915476. J Enzyme Inhib Med Chem. 2009. PMID: 18608754 Free article.
58 results