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Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.
Pike VW, Taliani S, Lohith TG, Owen DR, Pugliesi I, Da Pozzo E, Hong J, Zoghbi SS, Gunn RN, Parker CA, Rabiner EA, Fujita M, Innis RB, Martini C, Da Settimo F. Pike VW, et al. Among authors: owen dr. J Med Chem. 2011 Jan 13;54(1):366-73. doi: 10.1021/jm101230g. Epub 2010 Dec 6. J Med Chem. 2011. PMID: 21133364 Free PMC article.
Mixed-affinity binding in humans with 18-kDa translocator protein ligands.
Owen DR, Gunn RN, Rabiner EA, Bennacef I, Fujita M, Kreisl WC, Innis RB, Pike VW, Reynolds R, Matthews PM, Parker CA. Owen DR, et al. J Nucl Med. 2011 Jan;52(1):24-32. doi: 10.2967/jnumed.110.079459. Epub 2010 Dec 13. J Nucl Med. 2011. PMID: 21149489 Free PMC article.
Towards molecular imaging of multiple sclerosis.
Owen DR, Piccini P, Matthews PM. Owen DR, et al. Mult Scler. 2011 Mar;17(3):262-72. doi: 10.1177/1352458510390070. Epub 2011 Jan 6. Mult Scler. 2011. PMID: 21212087 Review.
Imaging of atherosclerosis.
Owen DR, Lindsay AC, Choudhury RP, Fayad ZA. Owen DR, et al. Annu Rev Med. 2011;62:25-40. doi: 10.1146/annurev-med-041709-133809. Annu Rev Med. 2011. PMID: 21226610 Free PMC article. Review.
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.
Owen DR, Yeo AJ, Gunn RN, Song K, Wadsworth G, Lewis A, Rhodes C, Pulford DJ, Bennacef I, Parker CA, StJean PL, Cardon LR, Mooser VE, Matthews PM, Rabiner EA, Rubio JP. Owen DR, et al. J Cereb Blood Flow Metab. 2012 Jan;32(1):1-5. doi: 10.1038/jcbfm.2011.147. Epub 2011 Oct 19. J Cereb Blood Flow Metab. 2012. PMID: 22008728 Free PMC article.
193 results