Okochi M - Search Results

1

Sigma-1Rs are upregulated via PERK/eIF2α/ATF4 pathway and execute protective function in ER stress.

Mitsuda T, Omi T, Tanimukai H, Sakagami Y, Tagami S, Okochi M, Kudo T, Takeda M. Mitsuda T, et al. Among authors: okochi m. Biochem Biophys Res Commun. 2011 Nov 25;415(3):519-25. doi: 10.1016/j.bbrc.2011.10.113. Epub 2011 Nov 3. Biochem Biophys Res Commun. 2011. PMID: 22079628

2

FAD-linked presenilin-1 mutants impede translation regulation under ER stress.

Yasuda Y, Kudo T, Katayama T, Imaizumi K, Yatera M, Okochi M, Yamamori H, Matsumoto N, Kida T, Fukumori A, Okumura M, Tohyama M, Takeda M. Yasuda Y, et al. Among authors: okochi m. Biochem Biophys Res Commun. 2002 Aug 16;296(2):313-8. doi: 10.1016/s0006-291x(02)00859-8. Biochem Biophys Res Commun. 2002. PMID: 12163019

3

Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

Okochi M, Steiner H, Fukumori A, Tanii H, Tomita T, Tanaka T, Iwatsubo T, Kudo T, Takeda M, Haass C. Okochi M, et al. EMBO J. 2002 Oct 15;21(20):5408-16. doi: 10.1093/emboj/cdf541. EMBO J. 2002. PMID: 12374741 Free PMC article.

4

The unfolded protein response is involved in the pathology of Alzheimer's disease.

Kudo T, Katayama T, Imaizumi K, Yasuda Y, Yatera M, Okochi M, Tohyama M, Takeda M. Kudo T, et al. Among authors: okochi m. Ann N Y Acad Sci. 2002 Nov;977:349-55. doi: 10.1111/j.1749-6632.2002.tb04837.x. Ann N Y Acad Sci. 2002. PMID: 12480772

5

[The amyloid beta protein generating mechanism simultaneously generates several other peptides in Alzheimer disease--discovery of new notch-beta peptide and the possibility of its use as a marker for the diagnosis of Alzheimer disease].

Okochi M, Takeda M. Okochi M, et al. Seishin Shinkeigaku Zasshi. 2003;105(1):87-96. Seishin Shinkeigaku Zasshi. 2003. PMID: 12701215 Review. Japanese. No abstract available.

6

[Familial Alzheimer's disease by beta-amyloid protein precursor (beta APP) mutations].

Okochi M, Takeda M. Okochi M, et al. Nihon Rinsho. 2004 Jan;62 Suppl:86-9. Nihon Rinsho. 2004. PMID: 15011326 Review. Japanese. No abstract available.

7

[Biological markers for diagnosis of Alzheimer's disease].

Takeda M, Tanaka T, Kudo T, Okochi M, Kamino A, Tagami S. Takeda M, et al. Among authors: okochi m. Seishin Shinkeigaku Zasshi. 2004;106(12):1610-4. Seishin Shinkeigaku Zasshi. 2004. PMID: 15770965 Review. Japanese. No abstract available.

8

Secretion of the Notch-1 Abeta-like peptide during Notch signaling.

Okochi M, Fukumori A, Jiang J, Itoh N, Kimura R, Steiner H, Haass C, Tagami S, Takeda M. Okochi M, et al. J Biol Chem. 2006 Mar 24;281(12):7890-8. doi: 10.1074/jbc.M513250200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16434391 Free article.

9

Development of new screening system for Alzheimer disease, in vitro Abeta sink assay, to identify the dissociation of soluble Abeta from fibrils.

Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara T, Morishita R. Sato N, et al. Among authors: okochi m. Neurobiol Dis. 2006 Jun;22(3):487-95. doi: 10.1016/j.nbd.2005.12.010. Epub 2006 Feb 20. Neurobiol Dis. 2006. PMID: 16488151

10

Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.

Fukumori A, Okochi M, Tagami S, Jiang J, Itoh N, Nakayama T, Yanagida K, Ishizuka-Katsura Y, Morihara T, Kamino K, Tanaka T, Kudo T, Tanii H, Ikuta A, Haass C, Takeda M. Fukumori A, et al. Among authors: okochi m. Biochemistry. 2006 Apr 18;45(15):4907-14. doi: 10.1021/bi052412w. Biochemistry. 2006. PMID: 16605258

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