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131 results

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Page 1
Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier.
Rohner A, Spilker ME, Lam JL, Pascual B, Bartkowski D, Li QJ, Yang AH, Stevens G, Xu M, Wells PA, Planken S, Nair S, Sun S. Rohner A, et al. Among authors: pascual b. Mol Cancer Ther. 2012 Jan;11(1):57-65. doi: 10.1158/1535-7163.MCT-11-0691. Epub 2011 Nov 14. Mol Cancer Ther. 2012. PMID: 22084163
A novel CXCR4 antagonist IgG1 antibody (PF-06747143) for the treatment of hematologic malignancies.
Liu SH, Gu Y, Pascual B, Yan Z, Hallin M, Zhang C, Fan C, Wang W, Lam J, Spilker ME, Yafawi R, Blasi E, Simmons B, Huser N, Ho WH, Lindquist K, Tran TT, Kudaravalli J, Ma JT, Jimenez G, Barman I, Brown C, Chin SM, Costa MJ, Shelton D, Smeal T, Fantin VR, Pernasetti F. Liu SH, et al. Among authors: pascual b. Blood Adv. 2017 Jun 21;1(15):1088-1100. doi: 10.1182/bloodadvances.2016003921. eCollection 2017 Jun 27. Blood Adv. 2017. PMID: 29296751 Free PMC article.
4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.
Liu KK, Bagrodia S, Bailey S, Cheng H, Chen H, Gao L, Greasley S, Hoffman JE, Hu Q, Johnson TO, Knighton D, Liu Z, Marx MA, Nambu MD, Ninkovic S, Pascual B, Rafidi K, Rodgers CM, Smith GL, Sun S, Wang H, Yang A, Yuan J, Zou A. Liu KK, et al. Among authors: pascual b. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6096-9. doi: 10.1016/j.bmcl.2010.08.045. Epub 2010 Aug 14. Bioorg Med Chem Lett. 2010. PMID: 20817449
Comparison of dynamic contrast-enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF-03084014 and sunitinib.
Zhang CC, Yan Z, Giddabasappa A, Lappin PB, Painter CL, Zhang Q, Li G, Goodman J, Simmons B, Pascual B, Lee J, Levkoff T, Nichols T, Xie Z. Zhang CC, et al. Among authors: pascual b. Cancer Med. 2014 Jun;3(3):462-71. doi: 10.1002/cam4.215. Epub 2014 Feb 27. Cancer Med. 2014. PMID: 24573979 Free PMC article.
Gemtuzumab Ozogamicin (GO) Inclusion to Induction Chemotherapy Eliminates Leukemic Initiating Cells and Significantly Improves Survival in Mouse Models of Acute Myeloid Leukemia.
Zhang CC, Yan Z, Pascual B, Jackson-Fisher A, Huang DS, Zong Q, Elliott M, Fan C, Huser N, Lee J, Sung M, Sapra P. Zhang CC, et al. Among authors: pascual b. Neoplasia. 2018 Jan;20(1):1-11. doi: 10.1016/j.neo.2017.10.008. Epub 2017 Nov 21. Neoplasia. 2018. PMID: 29172076 Free PMC article.
Biological characterization of a heterodimer-selective retinoid X receptor modulator: potential benefits for the treatment of type 2 diabetes.
Leibowitz MD, Ardecky RJ, Boehm MF, Broderick CL, Carfagna MA, Crombie DL, D'Arrigo J, Etgen GJ, Faul MM, Grese TA, Havel H, Hein NI, Heyman RA, Jolley D, Klausing K, Liu S, Mais DE, Mapes CM, Marschke KB, Michellys PY, Montrose-Rafizadeh C, Ogilvie KM, Pascual B, Rungta D, Tyhonas JS, Urcan MS, Wardlow M, Yumibe N, Reifel-Miller A. Leibowitz MD, et al. Among authors: pascual b. Endocrinology. 2006 Feb;147(2):1044-53. doi: 10.1210/en.2005-0690. Epub 2005 Nov 3. Endocrinology. 2006. PMID: 16269450
Clinical Manifestations.
Aguzzoli CS, Povala G, Ferreira PCL, Lussier FZ, Bauer-Negrini G, Amaral L, Soares C, Ferrari-Souza JP, Zalzale H, Bellaver B, Rohden F, Abbas S, Leffa DT, Schilling LP, Zimmer ER, Tudorascu D, Pascual B, Gordon BA, Lowe VJ, Oh H, Soleimani-Meigooni DN, Rosa-Neto P, Baker SL, Pascoal TA. Aguzzoli CS, et al. Among authors: pascual b. Alzheimers Dement. 2024 Dec;20 Suppl 3:e092310. doi: 10.1002/alz.092310. Alzheimers Dement. 2024. PMID: 39750244
131 results