Mandema JW - Search Results

1

Model-based meta-analysis for comparative efficacy and safety: application in drug development and beyond.

Mandema JW, Gibbs M, Boyd RA, Wada DR, Pfister M. Mandema JW, et al. Clin Pharmacol Ther. 2011 Dec;90(6):766-9. doi: 10.1038/clpt.2011.242. Clin Pharmacol Ther. 2011. PMID: 22089340

2

A dose-response meta-analysis for quantifying relative efficacy of biologics in rheumatoid arthritis.

Mandema JW, Salinger DH, Baumgartner SW, Gibbs MA. Mandema JW, et al. Clin Pharmacol Ther. 2011 Dec;90(6):828-35. doi: 10.1038/clpt.2011.256. Epub 2011 Nov 2. Clin Pharmacol Ther. 2011. PMID: 22048227

3

Therapeutic index of anticoagulants for prevention of venous thromboembolism following orthopedic surgery: a dose-response meta-analysis.

Mandema JW, Boyd RA, DiCarlo LA. Mandema JW, et al. Clin Pharmacol Ther. 2011 Dec;90(6):820-7. doi: 10.1038/clpt.2011.232. Epub 2011 Nov 2. Clin Pharmacol Ther. 2011. PMID: 22048231

4

Pharmacodynamic model for acute tolerance development to the electroencephalographic effects of alfentanil in the rat.

Mandema JW, Wada DR. Mandema JW, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1185-94. J Pharmacol Exp Ther. 1995. PMID: 8531080

5

Model-based drug development: a rational approach to efficiently accelerate drug development.

Milligan PA, Brown MJ, Marchant B, Martin SW, van der Graaf PH, Benson N, Nucci G, Nichols DJ, Boyd RA, Mandema JW, Krishnaswami S, Zwillich S, Gruben D, Anziano RJ, Stock TC, Lalonde RL. Milligan PA, et al. Among authors: mandema jw. Clin Pharmacol Ther. 2013 Jun;93(6):502-14. doi: 10.1038/clpt.2013.54. Epub 2013 Mar 14. Clin Pharmacol Ther. 2013. PMID: 23588322

6

Direct Oral Anticoagulants Vs. Enoxaparin for Prevention of Venous Thromboembolism Following Orthopedic Surgery: A Dose-Response Meta-analysis.

Boyd RA, DiCarlo L, Mandema JW. Boyd RA, et al. Among authors: mandema jw. Clin Transl Sci. 2017 Jul;10(4):260-270. doi: 10.1111/cts.12471. Epub 2017 May 23. Clin Transl Sci. 2017. PMID: 28467656 Free PMC article.

7

Short-Term Efficacy Reliably Predicts Long-Term Clinical Benefit in Rheumatoid Arthritis Clinical Trials as Demonstrated by Model-Based Meta-Analysis.

Wang Y, Zhu R, Xiao J, Davis JC Jr, Mandema JW, Jin JY, Tang MT. Wang Y, et al. Among authors: mandema jw. J Clin Pharmacol. 2016 Jul;56(7):835-44. doi: 10.1002/jcph.668. Epub 2015 Dec 31. J Clin Pharmacol. 2016. PMID: 26517752 Free PMC article.

8

Quantitative Evaluations of Time-Course and Treatment Effects of Systemic Agents for Psoriasis: A Model-Based Meta-Analysis.

Checchio T, Ahadieh S, Gupta P, Mandema J, Puig L, Wolk R, Valdez H, Tan H, Krishnaswami S, Tallman A, Kaur M, Ito K. Checchio T, et al. Clin Pharmacol Ther. 2017 Dec;102(6):1006-1016. doi: 10.1002/cpt.732. Epub 2017 Jun 21. Clin Pharmacol Ther. 2017. PMID: 28480503 Free PMC article. Review.

9

Prediction of clinical irrelevance of PK differences in atorvastatin using PK/PD models derived from literature-based meta-analyses.

Vargo R, Adewale A, Behm MO, Mandema J, Kerbusch T. Vargo R, et al. Clin Pharmacol Ther. 2014 Jul;96(1):101-9. doi: 10.1038/clpt.2014.66. Epub 2014 Mar 28. Clin Pharmacol Ther. 2014. PMID: 24682029 Free PMC article.

10

Clinical Trial Simulation to Inform Phase 2: Comparison of Concentrated vs. Distributed First-in-Patient Study Designs in Psoriasis.

Dodds MG, Salinger DH, Mandema J, Gibbs JP, Gibbs MA. Dodds MG, et al. CPT Pharmacometrics Syst Pharmacol. 2013 Jul 24;2(7):e58. doi: 10.1038/psp.2013.32. CPT Pharmacometrics Syst Pharmacol. 2013. PMID: 23884206 Free PMC article.

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