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MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.
Kolbeck R, Kozhich A, Koike M, Peng L, Andersson CK, Damschroder MM, Reed JL, Woods R, Dall'acqua WW, Stephens GL, Erjefalt JS, Bjermer L, Humbles AA, Gossage D, Wu H, Kiener PA, Spitalny GL, Mackay CR, Molfino NA, Coyle AJ. Kolbeck R, et al. J Allergy Clin Immunol. 2010 Jun;125(6):1344-1353.e2. doi: 10.1016/j.jaci.2010.04.004. J Allergy Clin Immunol. 2010. PMID: 20513525
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia.
Laviolette M, Gossage DL, Gauvreau G, Leigh R, Olivenstein R, Katial R, Busse WW, Wenzel S, Wu Y, Datta V, Kolbeck R, Molfino NA. Laviolette M, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2013 Nov;132(5):1086-1096.e5. doi: 10.1016/j.jaci.2013.05.020. Epub 2013 Jul 16. J Allergy Clin Immunol. 2013. PMID: 23866823 Free PMC article. Clinical Trial.
Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study.
Castro M, Wenzel SE, Bleecker ER, Pizzichini E, Kuna P, Busse WW, Gossage DL, Ward CK, Wu Y, Wang B, Khatry DB, van der Merwe R, Kolbeck R, Molfino NA, Raible DG. Castro M, et al. Among authors: kolbeck r. Lancet Respir Med. 2014 Nov;2(11):879-890. doi: 10.1016/S2213-2600(14)70201-2. Epub 2014 Oct 8. Lancet Respir Med. 2014. PMID: 25306557 Clinical Trial.
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma.
Busse WW, Katial R, Gossage D, Sari S, Wang B, Kolbeck R, Coyle AJ, Koike M, Spitalny GL, Kiener PA, Geba GP, Molfino NA. Busse WW, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2010 Jun;125(6):1237-1244.e2. doi: 10.1016/j.jaci.2010.04.005. J Allergy Clin Immunol. 2010. PMID: 20513521 Clinical Trial.
Role of IgE in autoimmunity.
Sanjuan MA, Sagar D, Kolbeck R. Sanjuan MA, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2016 Jun;137(6):1651-1661. doi: 10.1016/j.jaci.2016.04.007. Epub 2016 Apr 27. J Allergy Clin Immunol. 2016. PMID: 27264000 Review.
Novel targeted therapies for eosinophilic disorders.
Wechsler ME, Fulkerson PC, Bochner BS, Gauvreau GM, Gleich GJ, Henkel T, Kolbeck R, Mathur SK, Ortega H, Patel J, Prussin C, Renzi P, Rothenberg ME, Roufosse F, Simon D, Simon HU, Wardlaw A, Weller PF, Klion AD. Wechsler ME, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2012 Sep;130(3):563-71. doi: 10.1016/j.jaci.2012.07.027. J Allergy Clin Immunol. 2012. PMID: 22935585 Free PMC article. Review.
Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection.
Kearley J, Silver JS, Sanden C, Liu Z, Berlin AA, White N, Mori M, Pham TH, Ward CK, Criner GJ, Marchetti N, Mustelin T, Erjefalt JS, Kolbeck R, Humbles AA. Kearley J, et al. Among authors: kolbeck r. Immunity. 2015 Mar 17;42(3):566-79. doi: 10.1016/j.immuni.2015.02.011. Immunity. 2015. PMID: 25786179 Free article.
145 results