Brown AL - Search Results

1

The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation.

Brown AL, Salerno DG, Sadras T, Engler GA, Kok CH, Wilkinson CR, Samaraweera SE, Sadlon TJ, Perugini M, Lewis ID, Gonda TJ, D'Andrea RJ. Brown AL, et al. Differentiation. 2012 Jan;83(1):47-59. doi: 10.1016/j.diff.2011.08.003. Epub 2011 Oct 8. Differentiation. 2012. PMID: 22099176 Free PMC article.

2

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.

Phan VT, Shultz DB, Truong BT, Blake TJ, Brown AL, Gonda TJ, Le Beau MM, Kogan SC. Phan VT, et al. Among authors: brown al. Mol Cell Biol. 2003 Jul;23(13):4573-85. doi: 10.1128/MCB.23.13.4573-4585.2003. Mol Cell Biol. 2003. PMID: 12808098 Free PMC article.

3

Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation.

Brown AL, Peters M, D'Andrea RJ, Gonda TJ. Brown AL, et al. Blood. 2004 Jan 15;103(2):507-16. doi: 10.1182/blood-2003-05-1435. Epub 2003 Sep 22. Blood. 2004. PMID: 14504109 Free article.

4

Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling.

Brown AL, Wilkinson CR, Waterman SR, Kok CH, Salerno DG, Diakiw SM, Reynolds B, Scott HS, Tsykin A, Glonek GF, Goodall GJ, Solomon PJ, Gonda TJ, D'Andrea RJ. Brown AL, et al. J Leukoc Biol. 2006 Aug;80(2):433-47. doi: 10.1189/jlb.0206112. Epub 2006 Jun 12. J Leukoc Biol. 2006. PMID: 16769770

5

Repression of Gadd45alpha by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation.

Perugini M, Kok CH, Brown AL, Wilkinson CR, Salerno DG, Young SM, Diakiw SM, Lewis ID, Gonda TJ, D'Andrea RJ. Perugini M, et al. Among authors: brown al. Leukemia. 2009 Apr;23(4):729-38. doi: 10.1038/leu.2008.349. Epub 2009 Jan 8. Leukemia. 2009. PMID: 19151789

6

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.

Powell JA, Thomas D, Barry EF, Kok CH, McClure BJ, Tsykin A, To LB, Brown A, Lewis ID, Herbert K, Goodall GJ, Speed TP, Asou N, Jacob B, Osato M, Haylock DN, Nilsson SK, D'Andrea RJ, Lopez AF, Guthridge MA. Powell JA, et al. Blood. 2009 Nov 26;114(23):4859-70. doi: 10.1182/blood-2009-02-204818. Epub 2009 Oct 5. Blood. 2009. PMID: 19805619 Free article.

7

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit.

Perugini M, Brown AL, Salerno DG, Booker GW, Stojkoski C, Hercus TR, Lopez AF, Hibbs ML, Gonda TJ, D'Andrea RJ. Perugini M, et al. Among authors: brown al. Blood. 2010 Apr 22;115(16):3346-53. doi: 10.1182/blood-2009-08-235846. Epub 2010 Feb 19. Blood. 2010. PMID: 20173116 Free PMC article.

8

Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML.

Kok CH, Brown AL, Ekert PG, D'Andrea RJ. Kok CH, et al. Among authors: brown al. Leukemia. 2010 Jun;24(6):1239-43. doi: 10.1038/leu.2010.85. Epub 2010 Apr 29. Leukemia. 2010. PMID: 20428200 No abstract available.

9

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia.

Hahn CN, Chong CE, Carmichael CL, Wilkins EJ, Brautigan PJ, Li XC, Babic M, Lin M, Carmagnac A, Lee YK, Kok CH, Gagliardi L, Friend KL, Ekert PG, Butcher CM, Brown AL, Lewis ID, To LB, Timms AE, Storek J, Moore S, Altree M, Escher R, Bardy PG, Suthers GK, D'Andrea RJ, Horwitz MS, Scott HS. Hahn CN, et al. Among authors: brown al. Nat Genet. 2011 Sep 4;43(10):1012-7. doi: 10.1038/ng.913. Nat Genet. 2011. PMID: 21892162 Free PMC article.

10

The granulocyte-associated transcription factor Krüppel-like factor 5 is silenced by hypermethylation in acute myeloid leukemia.

Diakiw SM, Kok CH, To LB, Lewis ID, Brown AL, D'Andrea RJ. Diakiw SM, et al. Among authors: brown al. Leuk Res. 2012 Jan;36(1):110-6. doi: 10.1016/j.leukres.2011.09.013. Epub 2011 Oct 11. Leuk Res. 2012. PMID: 21993314

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