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Proteolytic control of TGF-β co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics.
Delolme F, Anastasi C, Alcaraz LB, Mendoza V, Vadon-Le Goff S, Talantikite M, Capomaccio R, Mevaere J, Fortin L, Mazzocut D, Damour O, Zanella-Cléon I, Hulmes DJ, Overall CM, Valcourt U, Lopez-Casillas F, Moali C. Delolme F, et al. Cell Mol Life Sci. 2015 Mar;72(5):1009-27. doi: 10.1007/s00018-014-1733-x. Epub 2014 Sep 27. Cell Mol Life Sci. 2015. PMID: 25260970 Free PMC article.
Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets.
Bekhouche M, Leduc C, Dupont L, Janssen L, Delolme F, Vadon-Le Goff S, Smargiasso N, Baiwir D, Mazzucchelli G, Zanella-Cleon I, Dubail J, De Pauw E, Nusgens B, Hulmes DJ, Moali C, Colige A. Bekhouche M, et al. Among authors: delolme f. FASEB J. 2016 May;30(5):1741-56. doi: 10.1096/fj.15-279869. Epub 2016 Jan 6. FASEB J. 2016. PMID: 26740262 Free article.
-Bekhouche, M., Leduc, C., Dupont, L., Janssen, L., Delolme, F., Vadon-Le Goff, S., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Zanella-Cleon, I., Dubail, J., De Pauw, E., Nusgens, B., Hulmes, D. ...
-Bekhouche, M., Leduc, C., Dupont, L., Janssen, L., Delolme, F., Vadon-Le Goff, S., Smargiasso, N., Baiwir, D., Mazzucchelli, …
Quantification of Detergents Complexed with Membrane Proteins.
Chaptal V, Delolme F, Kilburg A, Magnard S, Montigny C, Picard M, Prier C, Monticelli L, Bornert O, Agez M, Ravaud S, Orelle C, Wagner R, Jawhari A, Broutin I, Pebay-Peyroula E, Jault JM, Kaback HR, le Maire M, Falson P. Chaptal V, et al. Among authors: delolme f. Sci Rep. 2017 Feb 8;7:41751. doi: 10.1038/srep41751. Sci Rep. 2017. PMID: 28176812 Free PMC article.
BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1.
Anastasi C, Rousselle P, Talantikite M, Tessier A, Cluzel C, Bachmann A, Mariano N, Dussoyer M, Alcaraz LB, Fortin L, Aubert A, Delolme F, El Kholti N, Armengaud J, Fournié P, Auxenfans C, Valcourt U, Goff SV, Moali C. Anastasi C, et al. Among authors: delolme f. Sci Signal. 2020 Jul 7;13(639):eaba3880. doi: 10.1126/scisignal.aba3880. Sci Signal. 2020. PMID: 32636307
Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases.
Bijakowski C, Vadon-Le Goff S, Delolme F, Bourhis JM, Lécorché P, Ruggiero F, Becker-Pauly C, Yiallouros I, Stöcker W, Dive V, Hulmes DJ, Moali C. Bijakowski C, et al. Among authors: delolme f. J Biol Chem. 2012 Sep 28;287(40):33581-93. doi: 10.1074/jbc.M112.380816. Epub 2012 Jul 23. J Biol Chem. 2012. PMID: 22825851 Free PMC article.
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