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Page 1
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis.
Dorhoi A, Nouailles G, Jörg S, Hagens K, Heinemann E, Pradl L, Oberbeck-Müller D, Duque-Correa MA, Reece ST, Ruland J, Brosch R, Tschopp J, Gross O, Kaufmann SH. Dorhoi A, et al. Among authors: ruland j. Eur J Immunol. 2012 Feb;42(2):374-84. doi: 10.1002/eji.201141548. Epub 2011 Dec 20. Eur J Immunol. 2012. PMID: 22101787 Free article.
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.
Werninghaus K, Babiak A, Gross O, Hölscher C, Dietrich H, Agger EM, Mages J, Mocsai A, Schoenen H, Finger K, Nimmerjahn F, Brown GD, Kirschning C, Heit A, Andersen P, Wagner H, Ruland J, Lang R. Werninghaus K, et al. Among authors: ruland j. J Exp Med. 2009 Jan 16;206(1):89-97. doi: 10.1084/jem.20081445. Epub 2009 Jan 12. J Exp Med. 2009. PMID: 19139169 Free PMC article.
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.
Gross O, Poeck H, Bscheider M, Dostert C, Hannesschläger N, Endres S, Hartmann G, Tardivel A, Schweighoffer E, Tybulewicz V, Mocsai A, Tschopp J, Ruland J. Gross O, et al. Among authors: ruland j. Nature. 2009 May 21;459(7245):433-6. doi: 10.1038/nature07965. Epub 2009 Apr 1. Nature. 2009. PMID: 19339971
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J. Poeck H, et al. Among authors: ruland j. Nat Immunol. 2010 Jan;11(1):63-9. doi: 10.1038/ni.1824. Epub 2009 Nov 15. Nat Immunol. 2010. PMID: 19915568
The adaptor molecule CARD9 is essential for tuberculosis control.
Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf HJ, Hanke K, Gross O, Ruland J, Kaufmann SH. Dorhoi A, et al. Among authors: ruland j. J Exp Med. 2010 Apr 12;207(4):777-92. doi: 10.1084/jem.20090067. Epub 2010 Mar 29. J Exp Med. 2010. PMID: 20351059 Free PMC article.
224 results