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125 results

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Page 1
Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic.
Hoveyda HR, Marsault E, Gagnon R, Mathieu AP, Vézina M, Landry A, Wang Z, Benakli K, Beaubien S, Saint-Louis C, Brassard M, Pinault JF, Ouellet L, Bhat S, Ramaseshan M, Peng X, Foucher L, Beauchemin S, Bhérer P, Veber DF, Peterson ML, Fraser GL. Hoveyda HR, et al. Among authors: ouellet l. J Med Chem. 2011 Dec 22;54(24):8305-20. doi: 10.1021/jm2007062. Epub 2011 Nov 22. J Med Chem. 2011. PMID: 22106937
Discovery of a new class of macrocyclic antagonists to the human motilin receptor.
Marsault E, Hoveyda HR, Peterson ML, Saint-Louis C, Landry A, Vézina M, Ouellet L, Wang Z, Ramaseshan M, Beaubien S, Benakli K, Beauchemin S, Déziel R, Peeters T, Fraser GL. Marsault E, et al. Among authors: ouellet l. J Med Chem. 2006 Nov 30;49(24):7190-7. doi: 10.1021/jm0606600. J Med Chem. 2006. PMID: 17125271
Efficient parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Gagnon R, Peterson ML, Vézina M, Saint-Louis C, Landry A, Pinault JF, Ouellet L, Beauchemin S, Beaubien S, Mathieu A, Benakli K, Wang Z, Brassard M, Lonergan D, Bilodeau F, Ramaseshan M, Fortin N, Lan R, Li S, Galaud F, Plourde V, Champagne M, Doucet A, Bhérer P, Gauthier M, Olsen G, Villeneuve G, Bhat S, Foucher L, Fortin D, Peng X, Bernard S, Drouin A, Déziel R, Berthiaume G, Dory YL, Fraser GL, Deslongchamps P. Marsault E, et al. Among authors: ouellet l. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4731-5. doi: 10.1016/j.bmcl.2008.06.085. Epub 2008 Jun 28. Bioorg Med Chem Lett. 2008. PMID: 18640834
High throughput solid phase parallel synthesis of macrocyclic peptidomimetics.
Marsault E, Hoveyda HR, Peterson ML, Gagnon R, Vézina M, Pinault JF, Landry A, Saint-Louis C, Ouellet LG, Beauchemin S, Benakli K, Beaubien S, Brassard M, Wang Z, Champagne M, Galaud F, Fortin N, Fortin D, Plourde V, Ramaseshan M, Bhat S, Bilodeau F, Lonergan D, Lan R, Li S, Berthiaume G, Foucher L, Peng X, Dory Y, Deslongchamps P. Marsault E, et al. Among authors: ouellet lg. Adv Exp Med Biol. 2009;611:15-6. doi: 10.1007/978-0-387-73657-0_7. Adv Exp Med Biol. 2009. PMID: 19400074 No abstract available.
Agent-Based Model of Combined Community- and Jail-Based Take-Home Naloxone Distribution.
Tatara E, Ozik J, Pollack HA, Schneider JA, Friedman SR, Harawa NT, Boodram B, Salisbury-Afshar E, Hotton A, Ouellet L, Mackesy-Amiti ME, Collier N, Macal CM. Tatara E, et al. Among authors: ouellet l. JAMA Netw Open. 2024 Dec 2;7(12):e2448732. doi: 10.1001/jamanetworkopen.2024.48732. JAMA Netw Open. 2024. PMID: 39656460 Free PMC article.
Cholinergic neurotransmission in the anterior cingulate cortex is associated with cognitive performance in healthy older adults: Baseline characteristics of the Improving Neurological Health in Aging via Neuroplasticity-based Computerized Exercise (INHANCE) trial.
de Figueiredo Pelegrino A, Attarha M, Toussaint PJ, Ouellet L, Grant SJ, Van Vleet T, de Villers-Sidani E. de Figueiredo Pelegrino A, et al. Among authors: ouellet l. medRxiv [Preprint]. 2024 Nov 1:2024.10.30.24316439. doi: 10.1101/2024.10.30.24316439. medRxiv. 2024. PMID: 39574863 Free PMC article. Preprint.
Strategies used to reduce harms associated with fentanyl exposure among rural people who use drugs: multi-site qualitative findings from the rural opioid initiative.
Walters SM, Baker R, Frank D, Fadanelli M, Rudolph AE, Zule W, Fredericksen RJ, Bolinski R, Sibley AL, Go VF, Ouellet LJ, Pho MT, Seal DW, Feinberg J, Smith G, Young AM, Stopka TJ. Walters SM, et al. Among authors: ouellet lj. Harm Reduct J. 2024 Aug 24;21(1):154. doi: 10.1186/s12954-024-01062-2. Harm Reduct J. 2024. PMID: 39182116 Free PMC article.
125 results