Lopes F - Search Results

1

Targeting the liver stage of malaria parasites: a yet unmet goal.

Rodrigues T, Prudêncio M, Moreira R, Mota MM, Lopes F. Rodrigues T, et al. Among authors: lopes f. J Med Chem. 2012 Feb 9;55(3):995-1012. doi: 10.1021/jm201095h. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22122518 Review. No abstract available.

2

Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials.

Araújo MJ, Bom J, Capela R, Casimiro C, Chambel P, Gomes P, Iley J, Lopes F, Morais J, Moreira R, de Oliveira E, do Rosário V, Vale N. Araújo MJ, et al. Among authors: lopes f. J Med Chem. 2005 Feb 10;48(3):888-92. doi: 10.1021/jm0494624. J Med Chem. 2005. PMID: 15689174

3

Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design.

Rodrigues T, Moreira R, Guedes RC, Iley J, Lopes F. Rodrigues T, et al. Among authors: lopes f. Arch Pharm (Weinheim). 2008 Jun;341(6):344-50. doi: 10.1002/ardp.200700250. Arch Pharm (Weinheim). 2008. PMID: 18442019

4

Artemisinin-dipeptidyl vinyl sulfone hybrid molecules: design, synthesis and preliminary SAR for antiplasmodial activity and falcipain-2 inhibition.

Capela R, Oliveira R, Gonçalves LM, Domingos A, Gut J, Rosenthal PJ, Lopes F, Moreira R. Capela R, et al. Among authors: lopes f. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3229-32. doi: 10.1016/j.bmcl.2009.04.100. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19435664 Free PMC article.

5

Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials.

Rodrigues T, Guedes RC, dos Santos DJ, Carrasco M, Gut J, Rosenthal PJ, Moreira R, Lopes F. Rodrigues T, et al. Among authors: lopes f. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3476-80. doi: 10.1016/j.bmcl.2009.05.017. Epub 2009 May 9. Bioorg Med Chem Lett. 2009. PMID: 19467600

6

New hope in the fight against malaria?

Rodrigues T, Moreira R, Lopes F. Rodrigues T, et al. Among authors: lopes f. Future Med Chem. 2011 Jan;3(1):1-3. doi: 10.4155/fmc.10.274. Future Med Chem. 2011. PMID: 21428820 No abstract available.

7

Bis{(E)-3-[(diethyl-methyl-ammonio)meth-yl]-N-[3-(N,N-dimethyl-sulfamo-yl)-1-methyl-pyridin-4-yl-idene]-4-methoxy-anilinium} tetra-iodide penta-hydrate.

Rodrigues T, Moreira R, Dacunha-Marinho B, Lopes F. Rodrigues T, et al. Among authors: lopes f. Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 10;65(Pt 2):o283-4. doi: 10.1107/S1600536809000324. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21581896 Free PMC article.

8

Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy.

Capela R, Cabal GG, Rosenthal PJ, Gut J, Mota MM, Moreira R, Lopes F, Prudêncio M. Capela R, et al. Among authors: lopes f. Antimicrob Agents Chemother. 2011 Oct;55(10):4698-706. doi: 10.1128/AAC.05133-11. Epub 2011 Aug 1. Antimicrob Agents Chemother. 2011. PMID: 21807973 Free PMC article.

9

Identification of new antimalarial leads by use of virtual screening against cytochrome bc₁.

Rodrigues T, Moreira R, Gut J, Rosenthal PJ, O Neill PM, Biagini GA, Lopes F, dos Santos DJ, Guedes RC. Rodrigues T, et al. Among authors: lopes f. Bioorg Med Chem. 2011 Nov 1;19(21):6302-8. doi: 10.1016/j.bmc.2011.09.004. Epub 2011 Sep 10. Bioorg Med Chem. 2011. PMID: 21958736

10

Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.

Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. Among authors: lopes f. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465

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