Jiang Y - Search Results

1

C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle.

Zhan W, Jiang Y, Sharma S, Brodie PJ, Bane S, Kingston DG, Liotta DC, Snyder JP. Zhan W, et al. Among authors: jiang y. Chemistry. 2011 Dec 23;17(52):14792-804. doi: 10.1002/chem.201102630. Epub 2011 Nov 30. Chemistry. 2011. PMID: 22127984 Free PMC article.

2

Design and synthesis of C6-C8 bridged epothilone A.

Zhan W, Jiang Y, Brodie PJ, Kingston DG, Liotta DC, Snyder JP. Zhan W, et al. Among authors: jiang y. Org Lett. 2008 Apr 17;10(8):1565-8. doi: 10.1021/ol800422q. Epub 2008 Mar 21. Org Lett. 2008. PMID: 18355076 Free PMC article.

3

Design, synthesis and biological evaluation of bridged epothilone D analogues.

Chen QH, Ganesh T, Brodie P, Slebodnick C, Jiang Y, Banerjee A, Bane S, Snyder JP, Kingston DG. Chen QH, et al. Among authors: jiang y. Org Biomol Chem. 2008 Dec 21;6(24):4542-52. doi: 10.1039/b814823f. Epub 2008 Nov 6. Org Biomol Chem. 2008. PMID: 19039362 Free PMC article.

4

Diastereomers of dibromo-7-epi-10-deacetylcephalomannine: crowded and cytotoxic taxanes exhibit halogen bonds.

Jiang Y, Alcaraz AA, Chen JM, Kobayashi H, Lu YJ, Snyder JP. Jiang Y, et al. J Med Chem. 2006 Mar 23;49(6):1891-9. doi: 10.1021/jm0509243. J Med Chem. 2006. PMID: 16539375

5

Bridging converts a noncytotoxic nor-paclitaxel derivative to a cytotoxic analogue by constraining it to the T-Taxol conformation.

Tang S, Yang C, Brodie P, Bane S, Ravindra R, Sharma S, Jiang Y, Snyder JP, Kingston DG. Tang S, et al. Among authors: jiang y. Org Lett. 2006 Aug 31;8(18):3983-6. doi: 10.1021/ol061438s. Org Lett. 2006. PMID: 16928054 Free PMC article.

6

Synthesis, biological activity and tubulin binding poses of 1-deoxy-9-(R)-dihydrotaxane analogs.

Yuan TH, Jiang Y, Wang XH, Wang DL, Bannerjee A, Bane S, Snyder JP, Lin HX. Yuan TH, et al. Among authors: jiang y. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1148-51. doi: 10.1016/j.bmcl.2008.12.091. Epub 2008 Dec 27. Bioorg Med Chem Lett. 2009. PMID: 19136258

7

Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction.

Chen QH, Ganesh T, Jiang Y, Banerjee A, Sharma S, Bane S, Snyder JP, Kingston DG. Chen QH, et al. Among authors: jiang y. Chem Commun (Camb). 2010 Mar 28;46(12):2019-21. doi: 10.1039/b926174e. Epub 2010 Feb 9. Chem Commun (Camb). 2010. PMID: 20221478 Free PMC article.

8

Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles.

Jecs E, Tahirovic YA, Wilson RJ, Miller EJ, Kim M, Truax V, Nguyen HH, Akins NS, Saindane M, Wang T, Sum CS, Cvijic ME, Schroeder GM, Burton SL, Derdeyn CA, Xu L, Jiang Y, Wilson LJ, Liotta DC. Jecs E, et al. Among authors: jiang y. J Med Chem. 2022 Mar 10;65(5):4058-4084. doi: 10.1021/acs.jmedchem.1c01564. Epub 2022 Feb 18. J Med Chem. 2022. PMID: 35179893

9

Amino-Heterocycle Tetrahydroisoquinoline CXCR4 Antagonists with Improved ADME Profiles via Late-Stage Buchwald Couplings.

Nguyen HH, Tahirovic YA, Truax VM, Wilson RJ, Jecs E, Miller EJ, Kim MB, Akins NS, Xu L, Jiang Y, Wang T, Sum CS, Cvijic ME, Schroeder GM, Wilson LJ, Liotta DC. Nguyen HH, et al. Among authors: jiang y. ACS Med Chem Lett. 2021 Oct 4;12(10):1605-1612. doi: 10.1021/acsmedchemlett.1c00449. eCollection 2021 Oct 14. ACS Med Chem Lett. 2021. PMID: 34676043 Free PMC article.

10

Multivalency-directed magic-ring [2](3)catenane by olefin metathesis.

Jiang Y, Zhu XZ, Chen CF. Jiang Y, et al. Chemistry. 2010 Dec 27;16(48):14285-9. doi: 10.1002/chem.201002111. Chemistry. 2010. PMID: 21117045 No abstract available.

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