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Dnmt3a is essential for hematopoietic stem cell differentiation.
Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, Godley LA, Li W, Goodell MA. Challen GA, et al. Among authors: liang s. Nat Genet. 2011 Dec 4;44(1):23-31. doi: 10.1038/ng.1009. Nat Genet. 2011. PMID: 22138693 Free PMC article.
The epigenome of AML stem and progenitor cells.
Yamazaki J, Estecio MR, Lu Y, Long H, Malouf GG, Graber D, Huo Y, Ramagli L, Liang S, Kornblau SM, Jelinek J, Issa JP. Yamazaki J, et al. Among authors: liang s. Epigenetics. 2013 Jan;8(1):92-104. doi: 10.4161/epi.23243. Epub 2012 Dec 18. Epigenetics. 2013. PMID: 23249680 Free PMC article.
Caloric restriction delays age-related methylation drift.
Maegawa S, Lu Y, Tahara T, Lee JT, Madzo J, Liang S, Jelinek J, Colman RJ, Issa JJ. Maegawa S, et al. Among authors: liang s. Nat Commun. 2017 Sep 14;8(1):539. doi: 10.1038/s41467-017-00607-3. Nat Commun. 2017. PMID: 28912502 Free PMC article.
Widespread and tissue specific age-related DNA methylation changes in mice.
Maegawa S, Hinkal G, Kim HS, Shen L, Zhang L, Zhang J, Zhang N, Liang S, Donehower LA, Issa JP. Maegawa S, et al. Among authors: liang s. Genome Res. 2010 Mar;20(3):332-40. doi: 10.1101/gr.096826.109. Epub 2010 Jan 27. Genome Res. 2010. PMID: 20107151 Free PMC article.
TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.
Yamazaki J, Jelinek J, Lu Y, Cesaroni M, Madzo J, Neumann F, He R, Taby R, Vasanthakumar A, Macrae T, Ostler KR, Kantarjian HM, Liang S, Estecio MR, Godley LA, Issa JP. Yamazaki J, et al. Among authors: liang s. Cancer Res. 2015 Jul 15;75(14):2833-43. doi: 10.1158/0008-5472.CAN-14-0739. Epub 2015 May 13. Cancer Res. 2015. PMID: 25972343 Free PMC article. Clinical Trial.
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