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WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.
Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, Schumacher VA, Harper SJ, Hinton DR, Bates DO, Ladomery MR. Amin EM, et al. Among authors: schumacher va. Cancer Cell. 2011 Dec 13;20(6):768-80. doi: 10.1016/j.ccr.2011.10.016. Cancer Cell. 2011. PMID: 22172722 Free PMC article.
Slow progressive FSGS associated with an F392L WT1 mutation.
Kaltenis P, Schumacher V, Jankauskiene A, Laurinavicius A, Royer-Pokora B. Kaltenis P, et al. Pediatr Nephrol. 2004 Mar;19(3):353-6. doi: 10.1007/s00467-003-1372-1. Epub 2004 Jan 27. Pediatr Nephrol. 2004. PMID: 14745636
Clinical relevance of mutations in the Wilms tumor suppressor 1 gene WT1 and the cadherin-associated protein beta1 gene CTNNB1 for patients with Wilms tumors: results of long-term surveillance of 71 patients from International Society of Pediatric Oncology Study 9/Society for Pediatric Oncology.
Royer-Pokora B, Weirich A, Schumacher V, Uschkereit C, Beier M, Leuschner I, Graf N, Autschbach F, Schneider D, von Harrach M. Royer-Pokora B, et al. Cancer. 2008 Sep 1;113(5):1080-9. doi: 10.1002/cncr.23672. Cancer. 2008. PMID: 18618575 Free article.
Impaired glomerular maturation and lack of VEGF165b in Denys-Drash syndrome.
Schumacher VA, Jeruschke S, Eitner F, Becker JU, Pitschke G, Ince Y, Miner JH, Leuschner I, Engers R, Everding AS, Bulla M, Royer-Pokora B. Schumacher VA, et al. J Am Soc Nephrol. 2007 Mar;18(3):719-29. doi: 10.1681/ASN.2006020124. Epub 2007 Jan 31. J Am Soc Nephrol. 2007. PMID: 17267748
WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.
Schumacher VA, Schlötzer-Schrehardt U, Karumanchi SA, Shi X, Zaia J, Jeruschke S, Zhang D, Pavenstädt H, Drenckhan A, Amann K, Ng C, Hartwig S, Ng KH, Ho J, Kreidberg JA, Taglienti M, Royer-Pokora B, Ai X. Schumacher VA, et al. J Am Soc Nephrol. 2011 Jul;22(7):1286-96. doi: 10.1681/ASN.2010080860. Epub 2011 Jun 30. J Am Soc Nephrol. 2011. PMID: 21719793 Free PMC article.
Evidence for susceptibility genes to familial Wilms tumour in addition to WT1, FWT1 and FWT2.
Rapley EA, Barfoot R, Bonaïti-Pellié C, Chompret A, Foulkes W, Perusinghe N, Reeve A, Royer-Pokora B, Schumacher V, Shelling A, Skeen J, de Tourreil S, Weirich A, Pritchard-Jones K, Stratton MR, Rahman N. Rapley EA, et al. Br J Cancer. 2000 Jul;83(2):177-83. doi: 10.1054/bjoc.2000.1283. Br J Cancer. 2000. PMID: 10901367 Free PMC article.
50 results