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Potent inhibitors of LpxC for the treatment of Gram-negative infections.
Brown MF, Reilly U, Abramite JA, Arcari JT, Oliver R, Barham RA, Che Y, Chen JM, Collantes EM, Chung SW, Desbonnet C, Doty J, Doroski M, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, Marra A, McElroy E, Melnick M, Menard CA, Montgomery JI, Mullins L, Noe MC, O'Donnell J, Penzien J, Plummer MS, Price LM, Shanmugasundaram V, Thoma C, Uccello DP, Warmus JS, Wishka DG. Brown MF, et al. J Med Chem. 2012 Jan 26;55(2):914-23. doi: 10.1021/jm2014748. Epub 2012 Jan 11. J Med Chem. 2012. PMID: 22175825
Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections.
Montgomery JI, Brown MF, Reilly U, Price LM, Abramite JA, Arcari J, Barham R, Che Y, Chen JM, Chung SW, Collantes EM, Desbonnet C, Doroski M, Doty J, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, McAllister L, McElroy E, Menard CA, Mitton-Fry M, Mullins L, Noe MC, O'Donnell J, Oliver R, Penzien J, Plummer M, Shanmugasundaram V, Thoma C, Tomaras AP, Uccello DP, Vaz A, Wishka DG. Montgomery JI, et al. J Med Chem. 2012 Feb 23;55(4):1662-70. doi: 10.1021/jm2014875. Epub 2012 Feb 8. J Med Chem. 2012. PMID: 22257165
11-Ketotigogenin cellobioside (pamaqueside): a potent cholesterol absorption inhibitor in the hamster.
McCarthy PA, DeNinno MP, Morehouse LA, Chandler CE, Bangerter FW, Wilson TC, Urban FJ, Walinsky SW, Cosgrove PG, Duplantier K, Etienne JB, Fowler MA, Lambert JF, O'Donnell JP, Pezzullo SL, Watson HA Jr, Wilkins RW, Zaccaro LM, Zawistoski MP. McCarthy PA, et al. J Med Chem. 1996 May 10;39(10):1935-7. doi: 10.1021/jm960123n. J Med Chem. 1996. PMID: 8642548 No abstract available.
Bleeding disorder of unknown cause: an illustrated review on current practice, knowledge gaps, and future perspectives.
Monard ALL, Mussert CMA, van Duijl TT, Kruip MJHA, Henskens YMC, van den Biggelaar M, Schutgens REG, Schols SEM, Fijnvandraat KJ, Meijer K, den Exter PL, Nieuwenhuizen L, van Moort I, Baker RI, O'Donnell JS, Cnossen MH, Heubel-Moenen FCJI. Monard ALL, et al. Among authors: o donnell js. Res Pract Thromb Haemost. 2024 Nov 13;8(8):102625. doi: 10.1016/j.rpth.2024.102625. eCollection 2024 Nov. Res Pract Thromb Haemost. 2024. PMID: 39687924 Free PMC article.
Empagliflozin to prevent worsening of left ventricular volumes and systolic function after myocardial infarction (EMPRESS-MI).
Carberry J, Petrie MC, Lee MMY, Stanley B, Brooksbank KJM, Campbell RT, Good R, Jhund PS, Kellman P, Lang NN, Lindsay MM, Mangion K, Gardner RS, Mark PB, Meyer B, O'Donnell J, Orchard V, Shaukat A, Watkins S, McConnachie A, McMurray JJV, Welsh P, Sattar N, Berry C, Docherty KF. Carberry J, et al. Among authors: o donnell j. Eur J Heart Fail. 2024 Dec 15. doi: 10.1002/ejhf.3560. Online ahead of print. Eur J Heart Fail. 2024. PMID: 39675781
2,215 results