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Inhibition of RhoA reduces propofol-mediated growth cone collapse, axonal transport impairment, loss of synaptic connectivity, and behavioural deficits.
Pearn ML, Schilling JM, Jian M, Egawa J, Wu C, Mandyam CD, Fannon-Pavlich MJ, Nguyen U, Bertoglio J, Kodama M, Mahata SK, DerMardirossian C, Lemkuil BP, Han R, Mobley WC, Patel HH, Patel PM, Head BP. Pearn ML, et al. Br J Anaesth. 2018 Apr;120(4):745-760. doi: 10.1016/j.bja.2017.12.033. Epub 2018 Feb 15. Br J Anaesth. 2018. PMID: 29576115 Free PMC article.
Loss of caveolin-1 accelerates neurodegeneration and aging.
Head BP, Peart JN, Panneerselvam M, Yokoyama T, Pearn ML, Niesman IR, Bonds JA, Schilling JM, Miyanohara A, Headrick J, Ali SS, Roth DM, Patel PM, Patel HH. Head BP, et al. Among authors: pearn ml. PLoS One. 2010 Dec 23;5(12):e15697. doi: 10.1371/journal.pone.0015697. PLoS One. 2010. PMID: 21203469 Free PMC article.
22 results