Trimmer P - Search Results

1

The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrity.

Boscolo A, Starr JA, Sanchez V, Lunardi N, DiGruccio MR, Ori C, Erisir A, Trimmer P, Bennett J, Jevtovic-Todorovic V. Boscolo A, et al. Among authors: trimmer p. Neurobiol Dis. 2012 Mar;45(3):1031-41. doi: 10.1016/j.nbd.2011.12.022. Epub 2011 Dec 14. Neurobiol Dis. 2012. PMID: 22198380 Free PMC article.

2

Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture.

Trimmer PA, Keeney PM, Borland MK, Simon FA, Almeida J, Swerdlow RH, Parks JP, Parker WD Jr, Bennett JP Jr. Trimmer PA, et al. Neurobiol Dis. 2004 Feb;15(1):29-39. doi: 10.1016/j.nbd.2003.09.011. Neurobiol Dis. 2004. PMID: 14751768

3

The cybrid model of sporadic Parkinson's disease.

Trimmer PA, Bennett JP Jr. Trimmer PA, et al. Exp Neurol. 2009 Aug;218(2):320-5. doi: 10.1016/j.expneurol.2009.03.016. Epub 2009 Mar 26. Exp Neurol. 2009. PMID: 19328199 Free PMC article. Review.

4

Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro.

Parks JK, Smith TS, Trimmer PA, Bennett JP Jr, Parker WD Jr. Parks JK, et al. Among authors: trimmer pa. J Neurochem. 2001 Feb;76(4):1050-6. doi: 10.1046/j.1471-4159.2001.00112.x. J Neurochem. 2001. PMID: 11181824 Free article.

5

Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity.

Trimmer PA, Smith TS, Jung AB, Bennett JP Jr. Trimmer PA, et al. Neurodegeneration. 1996 Sep;5(3):233-9. doi: 10.1006/neur.1996.0031. Neurodegeneration. 1996. PMID: 8910901

6

Mitochondrial toxins in models of neurodegenerative diseases. II: Elevated zif268 transcription and independent temporal regulation of striatal D1 and D2 receptor mRNAs and D1 and D2 receptor-binding sites in C57BL/6 mice during MPTP treatment.

Smith TS, Trimmer PA, Khan SM, Tinklepaugh DL, Bennett JP Jr. Smith TS, et al. Among authors: trimmer pa. Brain Res. 1997 Aug 15;765(2):189-97. doi: 10.1016/s0006-8993(97)00430-7. Brain Res. 1997. PMID: 9313891

7

Mitochondrial quality, dynamics and functional capacity in Parkinson's disease cybrid cell lines selected for Lewy body expression.

Cronin-Furman EN, Borland MK, Bergquist KE, Bennett JP Jr, Trimmer PA. Cronin-Furman EN, et al. Among authors: trimmer pa. Mol Neurodegener. 2013 Jan 26;8:6. doi: 10.1186/1750-1326-8-6. Mol Neurodegener. 2013. PMID: 23351342 Free PMC article.

8

Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies.

Trimmer PA, Borland MK, Keeney PM, Bennett JP Jr, Parker WD Jr. Trimmer PA, et al. J Neurochem. 2004 Feb;88(4):800-12. doi: 10.1046/j.1471-4159.2003.02168.x. J Neurochem. 2004. PMID: 14756800 Free article.

9

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP Jr. Keeney PM, et al. Among authors: trimmer pa. Hum Gene Ther. 2009 Aug;20(8):897-907. doi: 10.1089/hum.2009.023. Hum Gene Ther. 2009. PMID: 19374590 Free PMC article.

10

Abnormal mitochondrial morphology in sporadic Parkinson's and Alzheimer's disease cybrid cell lines.

Trimmer PA, Swerdlow RH, Parks JK, Keeney P, Bennett JP Jr, Miller SW, Davis RE, Parker WD Jr. Trimmer PA, et al. Exp Neurol. 2000 Mar;162(1):37-50. doi: 10.1006/exnr.2000.7333. Exp Neurol. 2000. PMID: 10716887

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