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251 results

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Variants in the 3' untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner.
Amin AS, Giudicessi JR, Tijsen AJ, Spanjaart AM, Reckman YJ, Klemens CA, Tanck MW, Kapplinger JD, Hofman N, Sinner MF, Müller M, Wijnen WJ, Tan HL, Bezzina CR, Creemers EE, Wilde AA, Ackerman MJ, Pinto YM. Amin AS, et al. Among authors: bezzina cr. Eur Heart J. 2012 Mar;33(6):714-23. doi: 10.1093/eurheartj/ehr473. Epub 2011 Dec 23. Eur Heart J. 2012. PMID: 22199116 Free PMC article.
A single Na(+) channel mutation causing both long-QT and Brugada syndromes.
Bezzina C, Veldkamp MW, van Den Berg MP, Postma AV, Rook MB, Viersma JW, van Langen IM, Tan-Sindhunata G, Bink-Boelkens MT, van Der Hout AH, Mannens MM, Wilde AA. Bezzina C, et al. Circ Res. 1999 Dec 3-17;85(12):1206-13. doi: 10.1161/01.res.85.12.1206. Circ Res. 1999. PMID: 10590249
A sodium-channel mutation causes isolated cardiac conduction disease.
Tan HL, Bink-Boelkens MT, Bezzina CR, Viswanathan PC, Beaufort-Krol GC, van Tintelen PJ, van den Berg MP, Wilde AA, Balser JR. Tan HL, et al. Among authors: bezzina cr. Nature. 2001 Feb 22;409(6823):1043-7. doi: 10.1038/35059090. Nature. 2001. PMID: 11234013
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients.
Smits JP, Eckardt L, Probst V, Bezzina CR, Schott JJ, Remme CA, Haverkamp W, Breithardt G, Escande D, Schulze-Bahr E, LeMarec H, Wilde AA. Smits JP, et al. Among authors: bezzina cr. J Am Coll Cardiol. 2002 Jul 17;40(2):350-6. doi: 10.1016/s0735-1097(02)01962-9. J Am Coll Cardiol. 2002. PMID: 12106943 Free article.
Pharmacological rescue of mutant ion channels.
Bezzina CR, Tan HL. Bezzina CR, et al. Cardiovasc Res. 2002 Aug 1;55(2):229-32. doi: 10.1016/s0008-6363(02)00486-8. Cardiovasc Res. 2002. PMID: 12123759 No abstract available.
251 results