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Page 1
Response from the Canadian Children Inflammatory Bowel Disease Network to the US Food and Drug Administration Draft Guidance for Industry on pediatric inflammatory bowel disease: developing drugs for treatment.
Wine E, deBruyn J, Crowley E, Griffiths AM; Canadian Children IBD Network. Wine E, et al. J Can Assoc Gastroenterol. 2024 Oct 12;7(6):397-398. doi: 10.1093/jcag/gwae034. eCollection 2024 Dec. J Can Assoc Gastroenterol. 2024. PMID: 39679099 Free PMC article. No abstract available.
Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease.
Lee SH, Bushra M, Qiu L, Griffiths AM, Turpin W, Croitoru K; Crohn’s Colitis Canada Genetic Environmental And Microbial Consortium; Abreu M, Beck P, Bernstein C, Croitoru K, Dieleman L, Feagan B, Griffiths A, Guttman D, Jacobson K, Kaplan G, Krause DO, Madsen K, Marshall J, Moayyedi P, Ropeleski M, Seidman E, Silverberg M, Snapper S, Stadnyk A, Steinhart AH, Surette M, Turner D, Walters T, Vallance B, Aumais G, Bitton A, Cino M, Critch J, Denson L, Deslandres C, El-Matary W, Herfarth H, Higgins P, Huynh HQ, Hyams J, Mack D, McGrath J, Otley A, Panancionne R, Abreu M, Aumais G, Baldassano R, Bernstein C, Cino M, Denson L, Deslandres C, El-Matary W, Griffiths AM, Hedin C, Herfarth H, Higgins P, Hussey S, Huynh HQ, Jacobson K, Keljo D, Kevans D, Lees C, Mack D, Marshall J, McGrath J, Murthy S, Otley A, Panaccione R, Parekh N, Plamondon S, Radford-Smith G, Ropeleski M, Rosh J, Rubin D, Schultz M, Seidman E, Siegel C, Snapper S, Steinhart AH, Turner D. Lee SH, et al. Among authors: critch j. Gastroenterology. 2024 Oct 9:S0016-5085(24)05539-2. doi: 10.1053/j.gastro.2024.09.033. Online ahead of print. Gastroenterology. 2024. PMID: 39384162 Free article. No abstract available.
Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease.
Olivera PA, Martinez-Lozano H, Leibovitzh H, Xue M, Neustaeter A, Espin-Garcia O, Xu W, Madsen KL, Guttman DS, Bernstein CN, Yerushalmi B, Hyams JS, Abreu MT, Marshall JK, Wrobel I, Mack DR, Jacobson K, Bitton A, Aumais G, Panacionne R, Dieleman LA, Silverberg MS, Steinhart AH, Moayyedi P, Turner D, Griffiths AM, Turpin W, Lee SH, Croitoru K; Crohn’s and Colitis Canada (CCC) Genetic, Environmental, Microbial (GEM) Project Research Consortium. Olivera PA, et al. Gastroenterology. 2025 Jan;168(1):99-110.e2. doi: 10.1053/j.gastro.2024.08.031. Epub 2024 Sep 3. Gastroenterology. 2025. PMID: 39236898 Free article.
Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study.
Lee SH, Turpin W, Espin-Garcia O, Xu W, Croitoru K; Crohn's and Colitis Canada-Genetic, Environmental, Microbial (CCC-GEM) Project Research Consortium. Lee SH, et al. Gastroenterology. 2025 Jan;168(1):150-153.e4. doi: 10.1053/j.gastro.2024.08.021. Epub 2024 Aug 30. Gastroenterology. 2025. PMID: 39209122 Free article. No abstract available.
Landscape of TPMT and NUDT15 Pharmacogenetic Variation in a Cohort of Canadian Pediatric Inflammatory Bowel Disease Patients.
Kennedy AM, Griffiths AM, Muise AM, Walters TD, Ricciuto A, Huynh HQ, Wine E, Jacobson K, Lawrence S, Carman N, Mack DR, deBruyn JC, Otley AR, Deslandres C, El-Matary W, Zachos M, Benchimol EI, Critch J, Schneider R, Crowley E, Li M, Warner N, McGovern DPB, Li D, Haritunians T, Rudin S, Cohn I. Kennedy AM, et al. Among authors: critch j. Inflamm Bowel Dis. 2024 Dec 5;30(12):2418-2427. doi: 10.1093/ibd/izae109. Inflamm Bowel Dis. 2024. PMID: 38788739 Free PMC article.
Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project.
Xue M, Leibovitzh H, Jingcheng S, Neustaeter A, Dong M, Xu W, Espin-Garcia O, Griffiths AM, Steinhart AH, Turner D, Huynh HQ, Dieleman LA, Panaccione R, Aumais G, Bressler B, Bitton A, Murthy S, Marshall JK, Hyams JS, Otley A, Bernstein CN, Moayyedi P, El-Matary W, Fich A, Denson LA, Ropeleski MJ, Abreu MT, Deslandres C, Cino M, Avni-Biron I, Lee SH, Turpin W; CCC GEM Project Research Consortium; Croitoru K. Xue M, et al. Clin Gastroenterol Hepatol. 2024 Sep;22(9):1889-1897.e12. doi: 10.1016/j.cgh.2024.03.049. Epub 2024 May 16. Clin Gastroenterol Hepatol. 2024. PMID: 38759825
Adalimumab vs Infliximab in Luminal Pediatric Crohn's Disease: Comparable Outcomes in a Prospective Multicenter Cohort Study.
deBruyn JC, Huynh HQ, Griffiths AM, Jacobson K, Mack D, Deslandres C, El-Matary W, Otley AR, Church PC, Lawrence S, Wine E, Sherlock M, Critch J, Benchimol EI, Jantchou P, Rashid M, Carroll MW, Bax K, Ricciuto A, Carman N, Walters TD; Canadian Children IBD Network. deBruyn JC, et al. Among authors: critch j. Am J Gastroenterol. 2024 Mar 1;119(3):565-575. doi: 10.14309/ajg.0000000000002552. Epub 2023 Oct 3. Am J Gastroenterol. 2024. PMID: 37787642
Outcomes Following Acute Severe Colitis at Initial Presentation: A Multi-centre, Prospective, Paediatric Cohort Study.
Dhaliwal J, Tertigas D, Carman N, Lawrence S, Debruyn JC, Wine E, Church PC, Huynh HQ, Rashid M, El-Matary W, Deslandres C, Critch J, Ricciuto A, Carroll MW, Benchimol EI, Muise A, Jacobson K, Otley AR, Vallance B, Mack DR, Walters TD, Surette MG, Griffiths AM. Dhaliwal J, et al. Among authors: critch j. J Crohns Colitis. 2024 Feb 26;18(2):233-245. doi: 10.1093/ecco-jcc/jjad143. J Crohns Colitis. 2024. PMID: 37602969 Free PMC article.
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