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Page 1
Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging.
Bailey-Downs LC, Mitschelen M, Sosnowska D, Toth P, Pinto JT, Ballabh P, Valcarcel-Ares MN, Farley J, Koller A, Henthorn JC, Bass C, Sonntag WE, Ungvari Z, Csiszar A. Bailey-Downs LC, et al. J Gerontol A Biol Sci Med Sci. 2012 Apr;67(4):313-29. doi: 10.1093/gerona/glr164. Epub 2011 Oct 21. J Gerontol A Biol Sci Med Sci. 2012. PMID: 22021391 Free PMC article.
Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.
Ungvari Z, Tucsek Z, Sosnowska D, Toth P, Gautam T, Podlutsky A, Csiszar A, Losonczy G, Valcarcel-Ares MN, Sonntag WE, Csiszar A. Ungvari Z, et al. J Gerontol A Biol Sci Med Sci. 2013 Aug;68(8):877-91. doi: 10.1093/gerona/gls242. Epub 2012 Dec 13. J Gerontol A Biol Sci Med Sci. 2013. PMID: 23239824 Free PMC article.
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype.
Tarantini S, Valcarcel-Ares MN, Yabluchanskiy A, Tucsek Z, Hertelendy P, Kiss T, Gautam T, Zhang XA, Sonntag WE, de Cabo R, Farkas E, Elliott MH, Kinter MT, Deak F, Ungvari Z, Csiszar A. Tarantini S, et al. Among authors: valcarcel ares mn. J Gerontol A Biol Sci Med Sci. 2018 Jun 14;73(7):853-863. doi: 10.1093/gerona/glx177. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29905772 Free PMC article.
The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer.
Podlutsky A, Valcarcel-Ares MN, Yancey K, Podlutskaya V, Nagykaldi E, Gautam T, Miller RA, Sonntag WE, Csiszar A, Ungvari Z. Podlutsky A, et al. Geroscience. 2017 Apr;39(2):147-160. doi: 10.1007/s11357-017-9966-x. Epub 2017 Feb 23. Geroscience. 2017. PMID: 28233247 Free PMC article.
Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline.
Valcarcel-Ares MN, Tucsek Z, Kiss T, Giles CB, Tarantini S, Yabluchanskiy A, Balasubramanian P, Gautam T, Galvan V, Ballabh P, Richardson A, Freeman WM, Wren JD, Deak F, Ungvari Z, Csiszar A. Valcarcel-Ares MN, et al. J Gerontol A Biol Sci Med Sci. 2019 Feb 15;74(3):290-298. doi: 10.1093/gerona/gly127. J Gerontol A Biol Sci Med Sci. 2019. PMID: 29893815 Free PMC article.
IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.
Fulop GA, Ramirez-Perez FI, Kiss T, Tarantini S, Valcarcel Ares MN, Toth P, Yabluchanskiy A, Conley SM, Ballabh P, Martinez-Lemus LA, Ungvari Z, Csiszar A. Fulop GA, et al. Among authors: valcarcel ares mn. J Gerontol A Biol Sci Med Sci. 2019 Mar 14;74(4):446-454. doi: 10.1093/gerona/gly144. J Gerontol A Biol Sci Med Sci. 2019. PMID: 29931048 Free PMC article.
Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment.
Kiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z. Kiss T, et al. Among authors: valcarcel ares mn. Geroscience. 2019 Oct;41(5):619-630. doi: 10.1007/s11357-019-00074-2. Epub 2019 May 29. Geroscience. 2019. PMID: 31144244 Free PMC article.
IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.
Tarantini S, Giles CB, Wren JD, Ashpole NM, Valcarcel-Ares MN, Wei JY, Sonntag WE, Ungvari Z, Csiszar A. Tarantini S, et al. Age (Dordr). 2016 Aug;38(4):239-258. doi: 10.1007/s11357-016-9943-9. Epub 2016 Aug 26. Age (Dordr). 2016. PMID: 27566308 Free PMC article.
Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.
Tarantini S, Tucsek Z, Valcarcel-Ares MN, Toth P, Gautam T, Giles CB, Ballabh P, Wei JY, Wren JD, Ashpole NM, Sonntag WE, Ungvari Z, Csiszar A. Tarantini S, et al. Age (Dordr). 2016 Aug;38(4):273-289. doi: 10.1007/s11357-016-9931-0. Epub 2016 Sep 9. Age (Dordr). 2016. PMID: 27613724 Free PMC article.
23 results