Sabatini DM - Search Results

1

Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.

Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, Kang SA, Zhao J, Look AT, Sorger PK, Sabatini DM, Gray NS. Liu Q, et al. Among authors: sabatini dm. J Biol Chem. 2012 Mar 23;287(13):9742-9752. doi: 10.1074/jbc.M111.304485. Epub 2012 Jan 5. J Biol Chem. 2012. PMID: 22223645 Free PMC article.

2

Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.

Kumar V, Sabatini D, Pandey P, Gingras AC, Majumder PK, Kumar M, Yuan ZM, Carmichael G, Weichselbaum R, Sonenberg N, Kufe D, Kharbanda S. Kumar V, et al. J Biol Chem. 2000 Apr 14;275(15):10779-87. doi: 10.1074/jbc.275.15.10779. J Biol Chem. 2000. PMID: 10753870 Free article.

3

Huntingtin aggregates ask to be eaten.

Thoreen CC, Sabatini DM. Thoreen CC, et al. Among authors: sabatini dm. Nat Genet. 2004 Jun;36(6):553-4. doi: 10.1038/ng0604-553. Nat Genet. 2004. PMID: 15167929 No abstract available.

4

Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site.

Ali SM, Sabatini DM. Ali SM, et al. Among authors: sabatini dm. J Biol Chem. 2005 May 20;280(20):19445-8. doi: 10.1074/jbc.C500125200. Epub 2005 Apr 4. J Biol Chem. 2005. PMID: 15809305 Free article.

5

AMPK and p53 help cells through lean times.

Thoreen CC, Sabatini DM. Thoreen CC, et al. Among authors: sabatini dm. Cell Metab. 2005 May;1(5):287-8. doi: 10.1016/j.cmet.2005.04.009. Cell Metab. 2005. PMID: 16054073 Free article. Review.

6

Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex.

Sarbassov DD, Sabatini DM. Sarbassov DD, et al. Among authors: sabatini dm. J Biol Chem. 2005 Nov 25;280(47):39505-9. doi: 10.1074/jbc.M506096200. Epub 2005 Sep 23. J Biol Chem. 2005. PMID: 16183647 Free article.

7

Functional genomics identifies TOR-regulated genes that control growth and division.

Guertin DA, Guntur KV, Bell GW, Thoreen CC, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Curr Biol. 2006 May 23;16(10):958-70. doi: 10.1016/j.cub.2006.03.084. Curr Biol. 2006. PMID: 16713952 Free article.

8

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.

Frias MA, Thoreen CC, Jaffe JD, Schroder W, Sculley T, Carr SA, Sabatini DM. Frias MA, et al. Among authors: sabatini dm. Curr Biol. 2006 Sep 19;16(18):1865-70. doi: 10.1016/j.cub.2006.08.001. Epub 2006 Aug 17. Curr Biol. 2006. PMID: 16919458 Free article.

9

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. Guertin DA, et al. Among authors: sabatini dm. Dev Cell. 2006 Dec;11(6):859-71. doi: 10.1016/j.devcel.2006.10.007. Dev Cell. 2006. PMID: 17141160 Free article.

10

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Sancak Y, et al. Among authors: sabatini dm. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. Mol Cell. 2007. PMID: 17386266 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

292 results

Search Page

Filters