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Effect of the calmodulin inhibitor trifluoperazine on phosphorylation of P-glycoprotein and topoisomerase II: relationship to modulation of subcellular distribution, DNA damage and cytotoxicity of doxorubicin in multidrug resistant L1210 mouse leukemia cells.
Ganapathi R, Kamath N, Constantinou A, Grabowski D, Ford J, Anderson A. Ganapathi R, et al. Biochem Pharmacol. 1991 Jun 15;41(12):R21-6. doi: 10.1016/0006-2952(91)90115-l. Biochem Pharmacol. 1991. PMID: 1674871
Trifluoperazine modulation of resistance to the topoisomerase II inhibitor etoposide in doxorubicin resistant L1210 murine leukemia cells.
Kamath N, Grabowski D, Ford J, Drake F, Kerrigan D, Pommier Y, Ganapathi R. Kamath N, et al. Among authors: ganapathi r. Cancer Commun. 1991 Feb;3(2):37-44. Cancer Commun. 1991. PMID: 1995027
Murine leukemia L1210 cells selected for progressive resistance to doxorubicin (DOX) display both the multidrug resistant (MDR) phenotype and reductions in drug induced topoisomerase II-mediated DNA cleavage in nuclear extracts (Ganapathi, R.; Grabowski, D.; Ford, J …
Murine leukemia L1210 cells selected for progressive resistance to doxorubicin (DOX) display both the multidrug resistant (MDR) phenotype an …
Differential effect of the calmodulin inhibitor trifluoperazine in modulating cellular accumulation, retention and cytotoxicity of doxorubicin in progressively doxorubicin-resistant L1210 mouse leukemia cells. Lack of correlation between cellular doxorubicin levels and expression of resistance.
Ganapathi R, Grabowski D. Ganapathi R, et al. Biochem Pharmacol. 1988 Jan 15;37(2):185-93. doi: 10.1016/0006-2952(88)90716-2. Biochem Pharmacol. 1988. PMID: 3342075
140 results