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Page 1
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML.
Hirabayashi S, Flotho C, Moetter J, Heuser M, Hasle H, Gruhn B, Klingebiel T, Thol F, Schlegelberger B, Baumann I, Strahm B, Stary J, Locatelli F, Zecca M, Bergstraesser E, Dworzak M, van den Heuvel-Eibrink MM, De Moerloose B, Ogawa S, Niemeyer CM, Wlodarski MW; European Working Group of MDS in Childhood. Hirabayashi S, et al. Among authors: schlegelberger b. Blood. 2012 Mar 15;119(11):e96-9. doi: 10.1182/blood-2011-12-395087. Epub 2012 Jan 11. Blood. 2012. PMID: 22238327 Free article.
Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11.
Flotho C, Steinemann D, Mullighan CG, Neale G, Mayer K, Kratz CP, Schlegelberger B, Downing JR, Niemeyer CM. Flotho C, et al. Among authors: schlegelberger b. Oncogene. 2007 Aug 23;26(39):5816-21. doi: 10.1038/sj.onc.1210361. Epub 2007 Mar 12. Oncogene. 2007. PMID: 17353900
High-affinity neurotrophin receptors and ligands promote leukemogenesis.
Li Z, Beutel G, Rhein M, Meyer J, Koenecke C, Neumann T, Yang M, Krauter J, von Neuhoff N, Heuser M, Diedrich H, Göhring G, Wilkens L, Schlegelberger B, Ganser A, Baum C. Li Z, et al. Among authors: schlegelberger b. Blood. 2009 Feb 26;113(9):2028-37. doi: 10.1182/blood-2008-05-155200. Epub 2008 Dec 4. Blood. 2009. PMID: 19059881 Free PMC article.
Mutation analysis of the HAX1 gene in childhood myelodysplastic syndrome.
Steinemann D, Praulich I, Otto N, Göhring G, Niemeyer CM, Schlegelberger B. Steinemann D, et al. Among authors: schlegelberger b. Br J Haematol. 2009 May;145(4):533-4. doi: 10.1111/j.1365-2141.2009.07634.x. Br J Haematol. 2009. PMID: 19298594 Free article. No abstract available.
464 results