Harder KW - Search Results

1

The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells.

Nijnik A, Pistolic J, Cho P, Filewod NC, Falsafi R, Ramin A, Harder KW, Hancock RE. Nijnik A, et al. Among authors: harder kw. J Leukoc Biol. 2012 Apr;91(4):599-607. doi: 10.1189/jlb.0411191. Epub 2012 Jan 13. J Leukoc Biol. 2012. PMID: 22246800 Free PMC article. Clinical Trial.

2

Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells.

Krebs DL, Chehal MK, Sio A, Huntington ND, Da ML, Ziltener P, Inglese M, Kountouri N, Priatel JJ, Jones J, Tarlinton DM, Anderson GP, Hibbs ML, Harder KW. Krebs DL, et al. Among authors: harder kw. J Immunol. 2012 May 15;188(10):5094-105. doi: 10.4049/jimmunol.1103395. Epub 2012 Apr 9. J Immunol. 2012. PMID: 22491248

3

Lyn activity protects mice from DSS colitis and regulates the production of IL-22 from innate lymphoid cells.

Bishop JL, Roberts ME, Beer JL, Huang M, Chehal MK, Fan X, Fouser LA, Ma HL, Bacani JT, Harder KW. Bishop JL, et al. Among authors: harder kw. Mucosal Immunol. 2014 Mar;7(2):405-16. doi: 10.1038/mi.2013.60. Epub 2013 Sep 18. Mucosal Immunol. 2014. PMID: 24045577 Free article.

4

Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan.

Roberts ME, Barvalia M, Silva JAFD, Cederberg RA, Chu W, Wong A, Tai DC, Chen S, Matos I, Priatel JJ, Cullis PR, Harder KW. Roberts ME, et al. Among authors: harder kw. Circ Res. 2020 May 8;126(10):e61-e79. doi: 10.1161/CIRCRESAHA.119.315708. Epub 2020 Mar 10. Circ Res. 2020. PMID: 32151196 Free article.

5

Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.

Charest DL, Mordret G, Harder KW, Jirik F, Pelech SL. Charest DL, et al. Among authors: harder kw. Mol Cell Biol. 1993 Aug;13(8):4679-90. doi: 10.1128/mcb.13.8.4679-4690.1993. Mol Cell Biol. 1993. PMID: 7687743 Free PMC article.

6

Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion.

Harder KW, Moller NP, Peacock JW, Jirik FR. Harder KW, et al. J Biol Chem. 1998 Nov 27;273(48):31890-900. doi: 10.1074/jbc.273.48.31890. J Biol Chem. 1998. PMID: 9822658 Free article.

7

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M. Shio MT, et al. Among authors: harder kw. PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Epub 2009 Aug 21. PLoS Pathog. 2009. PMID: 19696895 Free PMC article.

8

Phosphatidylinositol-3 kinase activity in B cells is negatively regulated by Lyn tyrosine kinase.

Xu Y, Huntington ND, Harder KW, Nandurkar H, Hibbs ML, Tarlinton DM. Xu Y, et al. Among authors: harder kw. Immunol Cell Biol. 2012 Oct;90(9):903-11. doi: 10.1038/icb.2012.31. Epub 2012 Jul 10. Immunol Cell Biol. 2012. PMID: 22777522

9

Lyn deficiency leads to increased microbiota-dependent intestinal inflammation and susceptibility to enteric pathogens.

Roberts ME, Bishop JL, Fan X, Beer JL, Kum WW, Krebs DL, Huang M, Gill N, Priatel JJ, Finlay BB, Harder KW. Roberts ME, et al. Among authors: harder kw. J Immunol. 2014 Nov 15;193(10):5249-63. doi: 10.4049/jimmunol.1302832. Epub 2014 Oct 22. J Immunol. 2014. PMID: 25339668

10

Targeting Lyn regulates Snail family shuttling and inhibits metastasis.

Thaper D, Vahid S, Nip KM, Moskalev I, Shan X, Frees S, Roberts ME, Ketola K, Harder KW, Gregory-Evans C, Bishop JL, Zoubeidi A. Thaper D, et al. Among authors: harder kw. Oncogene. 2017 Jul 13;36(28):3964-3975. doi: 10.1038/onc.2017.5. Epub 2017 Mar 13. Oncogene. 2017. PMID: 28288135

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