Disney MD - Search Results

1

Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts.

Kumar A, Parkesh R, Sznajder LJ, Childs-Disney JL, Sobczak K, Disney MD. Kumar A, et al. Among authors: disney md. ACS Chem Biol. 2012 Mar 16;7(3):496-505. doi: 10.1021/cb200413a. Epub 2012 Jan 17. ACS Chem Biol. 2012. PMID: 22252896 Free PMC article.

2

Using selection to identify and chemical microarray to study the RNA internal loops recognized by 6'-N-acylated kanamycin A.

Disney MD, Childs-Disney JL. Disney MD, et al. Chembiochem. 2007 Apr 16;8(6):649-56. doi: 10.1002/cbic.200600569. Chembiochem. 2007. PMID: 17394189

3

"Supra"molecular recognition of Galectin 1.

Disney MD, Childs-Disney JL. Disney MD, et al. Chem Biol. 2007 Oct;14(10):1095-7. doi: 10.1016/j.chembiol.2007.10.002. Chem Biol. 2007. PMID: 17961821 No abstract available.

4

A small molecule microarray platform to select RNA internal loop-ligand interactions.

Childs-Disney JL, Wu M, Pushechnikov A, Aminova O, Disney MD. Childs-Disney JL, et al. Among authors: disney md. ACS Chem Biol. 2007 Nov 20;2(11):745-54. doi: 10.1021/cb700174r. Epub 2007 Nov 2. ACS Chem Biol. 2007. PMID: 17975888

5

A simple ligation-based method to increase the information density in sequencing reactions used to deconvolute nucleic acid selections.

Childs-Disney JL, Disney MD. Childs-Disney JL, et al. Among authors: disney md. RNA. 2008 Feb;14(2):390-4. doi: 10.1261/rna.576908. Epub 2007 Dec 7. RNA. 2008. PMID: 18065718 Free PMC article.

6

Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners.

Disney MD, Labuda LP, Paul DJ, Poplawski SG, Pushechnikov A, Tran T, Velagapudi SP, Wu M, Childs-Disney JL. Disney MD, et al. J Am Chem Soc. 2008 Aug 20;130(33):11185-94. doi: 10.1021/ja803234t. Epub 2008 Jul 25. J Am Chem Soc. 2008. PMID: 18652457

7

Two-dimensional combinatorial screening identifies specific 6'-acylated kanamycin A- and 6'-acylated neamine-RNA hairpin interactions.

Aminova O, Paul DJ, Childs-Disney JL, Disney MD. Aminova O, et al. Among authors: disney md. Biochemistry. 2008 Dec 2;47(48):12670-9. doi: 10.1021/bi8012615. Biochemistry. 2008. PMID: 18991404 Free PMC article.

8

Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intron.

Labuda LP, Pushechnikov A, Disney MD. Labuda LP, et al. Among authors: disney md. ACS Chem Biol. 2009 Apr 17;4(4):299-307. doi: 10.1021/cb800313m. ACS Chem Biol. 2009. PMID: 19278238 Free PMC article.

9

Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2.

Lee MM, Pushechnikov A, Disney MD. Lee MM, et al. Among authors: disney md. ACS Chem Biol. 2009 May 15;4(5):345-55. doi: 10.1021/cb900025w. ACS Chem Biol. 2009. PMID: 19348464 Free PMC article.

10

Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.

Pushechnikov A, Lee MM, Childs-Disney JL, Sobczak K, French JM, Thornton CA, Disney MD. Pushechnikov A, et al. Among authors: disney md. J Am Chem Soc. 2009 Jul 22;131(28):9767-79. doi: 10.1021/ja9020149. J Am Chem Soc. 2009. PMID: 19552411 Free PMC article.

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