Lorey SL - Search Results

1

Antiretroviral therapy reduces the magnitude and T cell receptor repertoire diversity of HIV-specific T cell responses without changing T cell clonotype dominance.

Conrad JA, Ramalingam RK, Duncan CB, Smith RM, Wei J, Barnett L, Simons BC, Lorey SL, Kalams SA. Conrad JA, et al. Among authors: lorey sl. J Virol. 2012 Apr;86(8):4213-21. doi: 10.1128/JVI.06000-11. Epub 2012 Jan 18. J Virol. 2012. PMID: 22258246 Free PMC article.

2

Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire.

Meyer-Olson D, Brady KW, Bartman MT, O'Sullivan KM, Simons BC, Conrad JA, Duncan CB, Lorey S, Siddique A, Draenert R, Addo M, Altfeld M, Rosenberg E, Allen TM, Walker BD, Kalams SA. Meyer-Olson D, et al. Blood. 2006 Mar 15;107(6):2373-83. doi: 10.1182/blood-2005-04-1636. Epub 2005 Dec 1. Blood. 2006. PMID: 16322475 Free PMC article.

3

Enhancement of human immunodeficiency virus (HIV)-specific CD8+ T cells in cerebrospinal fluid compared to those in blood among antiretroviral therapy-naive HIV-positive subjects.

Sadagopal S, Lorey SL, Barnett L, Basham R, Lebo L, Erdem H, Haman K, Avison M, Waddell K, Haas DW, Kalams SA. Sadagopal S, et al. Among authors: lorey sl. J Virol. 2008 Nov;82(21):10418-28. doi: 10.1128/JVI.01190-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715919 Free PMC article.

4

Despite biased TRBV gene usage against a dominant HLA B57-restricted epitope, TCR diversity can provide recognition of circulating epitope variants.

Simons BC, Vancompernolle SE, Smith RM, Wei J, Barnett L, Lorey SL, Meyer-Olson D, Kalams SA. Simons BC, et al. Among authors: lorey sl. J Immunol. 2008 Oct 1;181(7):5137-46. doi: 10.4049/jimmunol.181.7.5137. J Immunol. 2008. PMID: 18802118

5

Enhanced PD-1 expression by T cells in cerebrospinal fluid does not reflect functional exhaustion during chronic human immunodeficiency virus type 1 infection.

Sadagopal S, Lorey SL, Barnett L, Sutherland D, Basham R, Erdem H, Kalams SA, Haas DW. Sadagopal S, et al. Among authors: lorey sl. J Virol. 2010 Jan;84(1):131-40. doi: 10.1128/JVI.01181-09. J Virol. 2010. PMID: 19828602 Free PMC article.

6

Clonal expansion and TCR-independent differentiation shape the HIV-specific CD8+ effector-memory T-cell repertoire in vivo.

Meyer-Olson D, Simons BC, Conrad JA, Smith RM, Barnett L, Lorey SL, Duncan CB, Ramalingam R, Kalams SA. Meyer-Olson D, et al. Among authors: lorey sl. Blood. 2010 Jul 22;116(3):396-405. doi: 10.1182/blood-2009-11-254136. Epub 2010 Apr 27. Blood. 2010. PMID: 20424187 Free PMC article.

7

Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity.

Conrad JA, Ramalingam RK, Smith RM, Barnett L, Lorey SL, Wei J, Simons BC, Sadagopal S, Meyer-Olson D, Kalams SA. Conrad JA, et al. Among authors: lorey sl. J Immunol. 2011 Jun 15;186(12):6871-85. doi: 10.4049/jimmunol.1004234. Epub 2011 May 11. J Immunol. 2011. PMID: 21562156 Free PMC article.

8

B cell responses to HIV antigen are a potent correlate of viremia in HIV-1 infection and improve with PD-1 blockade.

Nicholas KJ, Zern EK, Barnett L, Smith RM, Lorey SL, Copeland CA, Sadagopal S, Kalams SA. Nicholas KJ, et al. Among authors: lorey sl. PLoS One. 2013 Dec 16;8(12):e84185. doi: 10.1371/journal.pone.0084185. eCollection 2013. PLoS One. 2013. PMID: 24358343 Free PMC article.

9

A common functional consequence of tumor-derived mutations within c-MYC.

Chakraborty AA, Scuoppo C, Dey S, Thomas LR, Lorey SL, Lowe SW, Tansey WP. Chakraborty AA, et al. Among authors: lorey sl. Oncogene. 2015 Apr 30;34(18):2406-9. doi: 10.1038/onc.2014.186. Epub 2014 Jul 7. Oncogene. 2015. PMID: 24998853 Free PMC article.

10

Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.

Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP. Thomas LR, et al. Mol Cell. 2015 May 7;58(3):440-52. doi: 10.1016/j.molcel.2015.02.028. Epub 2015 Mar 26. Mol Cell. 2015. PMID: 25818646 Free PMC article.

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