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The Q43L mutant of neuregulin 2β is a pan-ErbB receptor antagonist.
Wilson KJ, Mill CP, Gallo RM, Cameron EM, VanBrocklin H, Settleman J, Riese DJ. Wilson KJ, et al. Among authors: settleman j. Biochem J. 2012 Apr 1;443(1):133-44. doi: 10.1042/BJ20110921. Biochem J. 2012. PMID: 22216880 Free PMC article.
Modeling oncogene addiction using RNA interference.
Rothenberg SM, Engelman JA, Le S, Riese DJ 2nd, Haber DA, Settleman J. Rothenberg SM, et al. Among authors: settleman j. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12480-4. doi: 10.1073/pnas.0803217105. Epub 2008 Aug 18. Proc Natl Acad Sci U S A. 2008. PMID: 18711136 Free PMC article.
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Wilson TR, et al. Among authors: settleman j. Nature. 2012 Jul 26;487(7408):505-9. doi: 10.1038/nature11249. Nature. 2012. PMID: 22763448 Free PMC article.
238 results