Brenton JD - Search Results

1

Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium.

Archibald KM, Kulbe H, Kwong J, Chakravarty P, Temple J, Chaplin T, Flak MB, McNeish IA, Deen S, Brenton JD, Young BD, Balkwill F. Archibald KM, et al. Among authors: brenton jd. Oncogene. 2012 Nov 29;31(48):4987-95. doi: 10.1038/onc.2011.653. Epub 2012 Jan 23. Oncogene. 2012. PMID: 22266861 Free PMC article.

2

A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes.

Garcia MJ, Pole JC, Chin SF, Teschendorff A, Naderi A, Ozdag H, Vias M, Kranjac T, Subkhankulova T, Paish C, Ellis I, Brenton JD, Edwards PA, Caldas C. Garcia MJ, et al. Among authors: brenton jd. Oncogene. 2005 Aug 4;24(33):5235-45. doi: 10.1038/sj.onc.1208741. Oncogene. 2005. PMID: 15897872

3

A gene-expression signature to predict survival in breast cancer across independent data sets.

Naderi A, Teschendorff AE, Barbosa-Morais NL, Pinder SE, Green AR, Powe DG, Robertson JF, Aparicio S, Ellis IO, Brenton JD, Caldas C. Naderi A, et al. Among authors: brenton jd. Oncogene. 2007 Mar 1;26(10):1507-16. doi: 10.1038/sj.onc.1209920. Epub 2006 Aug 28. Oncogene. 2007. PMID: 16936776

4

Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B. Swanton C, et al. Among authors: brenton jd. Cancer Cell. 2007 Jun;11(6):498-512. doi: 10.1016/j.ccr.2007.04.011. Cancer Cell. 2007. PMID: 17560332 Free article.

5

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.

Ahmed AA, Etemadmoghadam D, Temple J, Lynch AG, Riad M, Sharma R, Stewart C, Fereday S, Caldas C, Defazio A, Bowtell D, Brenton JD. Ahmed AA, et al. Among authors: brenton jd. J Pathol. 2010 May;221(1):49-56. doi: 10.1002/path.2696. J Pathol. 2010. PMID: 20229506 Free PMC article.

6

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.

Cooke SL, Ng CK, Melnyk N, Garcia MJ, Hardcastle T, Temple J, Langdon S, Huntsman D, Brenton JD. Cooke SL, et al. Among authors: brenton jd. Oncogene. 2010 Sep 2;29(35):4905-13. doi: 10.1038/onc.2010.245. Epub 2010 Jun 28. Oncogene. 2010. PMID: 20581869 Free PMC article.

7

Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer.

Cooke SL, Temple J, Macarthur S, Zahra MA, Tan LT, Crawford RA, Ng CK, Jimenez-Linan M, Sala E, Brenton JD. Cooke SL, et al. Among authors: brenton jd. Br J Cancer. 2011 Jan 18;104(2):361-8. doi: 10.1038/sj.bjc.6605971. Epub 2010 Nov 9. Br J Cancer. 2011. PMID: 21063398 Free PMC article.

8

Rethinking ovarian cancer: recommendations for improving outcomes.

Vaughan S, Coward JI, Bast RC Jr, Berchuck A, Berek JS, Brenton JD, Coukos G, Crum CC, Drapkin R, Etemadmoghadam D, Friedlander M, Gabra H, Kaye SB, Lord CJ, Lengyel E, Levine DA, McNeish IA, Menon U, Mills GB, Nephew KP, Oza AM, Sood AK, Stronach EA, Walczak H, Bowtell DD, Balkwill FR. Vaughan S, et al. Among authors: brenton jd. Nat Rev Cancer. 2011 Sep 23;11(10):719-25. doi: 10.1038/nrc3144. Nat Rev Cancer. 2011. PMID: 21941283 Free PMC article.

9

The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer.

Ng CK, Cooke SL, Howe K, Newman S, Xian J, Temple J, Batty EM, Pole JC, Langdon SP, Edwards PA, Brenton JD. Ng CK, et al. Among authors: brenton jd. J Pathol. 2012 Apr;226(5):703-12. doi: 10.1002/path.3980. Epub 2012 Feb 9. J Pathol. 2012. PMID: 22183581

10

ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.

Tumbarello DA, Temple J, Brenton JD. Tumbarello DA, et al. Among authors: brenton jd. Mol Cancer. 2012 May 28;11:36. doi: 10.1186/1476-4598-11-36. Mol Cancer. 2012. PMID: 22640878 Free PMC article.

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