Xia M - Search Results

1

Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model.

Lock EF, Abdo N, Huang R, Xia M, Kosyk O, O'Shea SH, Zhou YH, Sedykh A, Tropsha A, Austin CP, Tice RR, Wright FA, Rusyn I. Lock EF, et al. Among authors: xia m. Toxicol Sci. 2012 Apr;126(2):578-88. doi: 10.1093/toxsci/kfs023. Epub 2012 Jan 19. Toxicol Sci. 2012. PMID: 22268004 Free PMC article.

2

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Among authors: xia m. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

3

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening.

Huang R, Southall N, Cho MH, Xia M, Inglese J, Austin CP. Huang R, et al. Among authors: xia m. Chem Res Toxicol. 2008 Mar;21(3):659-67. doi: 10.1021/tx700365e. Epub 2008 Feb 19. Chem Res Toxicol. 2008. PMID: 18281954 Free PMC article.

4

Compound cytotoxicity profiling using quantitative high-throughput screening.

Xia M, Huang R, Witt KL, Southall N, Fostel J, Cho MH, Jadhav A, Smith CS, Inglese J, Portier CJ, Tice RR, Austin CP. Xia M, et al. Environ Health Perspect. 2008 Mar;116(3):284-91. doi: 10.1289/ehp.10727. Environ Health Perspect. 2008. PMID: 18335092 Free PMC article.

5

A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker.

Cho MH, Niles A, Huang R, Inglese J, Austin CP, Riss T, Xia M. Cho MH, et al. Among authors: xia m. Toxicol In Vitro. 2008 Jun;22(4):1099-106. doi: 10.1016/j.tiv.2008.02.013. Epub 2008 Mar 4. Toxicol In Vitro. 2008. PMID: 18400464 Free PMC article.

6

Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory.

Xia M, Huang R, Guo V, Southall N, Cho MH, Inglese J, Austin CP, Nirenberg M. Xia M, et al. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2412-7. doi: 10.1073/pnas.0813020106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196967 Free PMC article.

7

Identification of chemical compounds that induce HIF-1alpha activity.

Xia M, Huang R, Sun Y, Semenza GL, Aldred SF, Witt KL, Inglese J, Tice RR, Austin CP. Xia M, et al. Toxicol Sci. 2009 Nov;112(1):153-63. doi: 10.1093/toxsci/kfp123. Epub 2009 Jun 5. Toxicol Sci. 2009. PMID: 19502547 Free PMC article.

8

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel.

Titus SA, Beacham D, Shahane SA, Southall N, Xia M, Huang R, Hooten E, Zhao Y, Shou L, Austin CP, Zheng W. Titus SA, et al. Among authors: xia m. Anal Biochem. 2009 Nov 1;394(1):30-8. doi: 10.1016/j.ab.2009.07.003. Epub 2009 Jul 5. Anal Biochem. 2009. PMID: 19583963 Free PMC article.

9

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries.

Johnson RL, Huang R, Jadhav A, Southall N, Wichterman J, MacArthur R, Xia M, Bi K, Printen J, Austin CP, Inglese J. Johnson RL, et al. Among authors: xia m. Mol Biosyst. 2009 Sep;5(9):1039-50. doi: 10.1039/b902021g. Epub 2009 Jun 19. Mol Biosyst. 2009. PMID: 19668870 Free PMC article.

10

Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features.

Huang R, Southall N, Xia M, Cho MH, Jadhav A, Nguyen DT, Inglese J, Tice RR, Austin CP. Huang R, et al. Among authors: xia m. Toxicol Sci. 2009 Dec;112(2):385-93. doi: 10.1093/toxsci/kfp231. Epub 2009 Oct 4. Toxicol Sci. 2009. PMID: 19805409 Free PMC article.

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