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Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures.
Diepold K, Bomans K, Wiedmann M, Zimmermann B, Petzold A, Schlothauer T, Mueller R, Moritz B, Stracke JO, Mølhøj M, Reusch D, Bulau P. Diepold K, et al. Among authors: wiedmann m. PLoS One. 2012;7(1):e30295. doi: 10.1371/journal.pone.0030295. Epub 2012 Jan 17. PLoS One. 2012. PMID: 22272329 Free PMC article.
Identification and monitoring of host cell proteins by mass spectrometry combined with high performance immunochemistry testing.
Bomans K, Lang A, Roedl V, Adolf L, Kyriosoglou K, Diepold K, Eberl G, Mølhøj M, Strauss U, Schmalz C, Vogel R, Reusch D, Wegele H, Wiedmann M, Bulau P. Bomans K, et al. Among authors: wiedmann m. PLoS One. 2013 Nov 27;8(11):e81639. doi: 10.1371/journal.pone.0081639. eCollection 2013. PLoS One. 2013. PMID: 24312330 Free PMC article.
Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes.
Haberger M, Bomans K, Diepold K, Hook M, Gassner J, Schlothauer T, Zwick A, Spick C, Kepert JF, Hienz B, Wiedmann M, Beck H, Metzger P, Mølhøj M, Knoblich C, Grauschopf U, Reusch D, Bulau P. Haberger M, et al. Among authors: wiedmann m. MAbs. 2014 Mar-Apr;6(2):327-39. doi: 10.4161/mabs.27876. Epub 2014 Jan 17. MAbs. 2014. PMID: 24441081 Free PMC article.
665 results