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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis.
Raychaudhuri S, Sandor C, Stahl EA, Freudenberg J, Lee HS, Jia X, Alfredsson L, Padyukov L, Klareskog L, Worthington J, Siminovitch KA, Bae SC, Plenge RM, Gregersen PK, de Bakker PI. Raychaudhuri S, et al. Among authors: klareskog l. Nat Genet. 2012 Jan 29;44(3):291-6. doi: 10.1038/ng.1076. Nat Genet. 2012. PMID: 22286218 Free PMC article.
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction.
Swanberg M, Lidman O, Padyukov L, Eriksson P, Akesson E, Jagodic M, Lobell A, Khademi M, Börjesson O, Lindgren CM, Lundman P, Brookes AJ, Kere J, Luthman H, Alfredsson L, Hillert J, Klareskog L, Hamsten A, Piehl F, Olsson T. Swanberg M, et al. Among authors: klareskog l. Nat Genet. 2005 May;37(5):486-94. doi: 10.1038/ng1544. Epub 2005 Apr 10. Nat Genet. 2005. PMID: 15821736
Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case-control study.
Sverdrup B, Källberg H, Bengtsson C, Lundberg I, Padyukov L, Alfredsson L, Klareskog L; Epidemiological Investigation of Rheumatoid Arthritis Study Group. Sverdrup B, et al. Among authors: klareskog l. Arthritis Res Ther. 2005;7(6):R1296-303. doi: 10.1186/ar1824. Epub 2005 Sep 23. Arthritis Res Ther. 2005. PMID: 16277683 Free PMC article.
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4.
Plenge RM, Padyukov L, Remmers EF, Purcell S, Lee AT, Karlson EW, Wolfe F, Kastner DL, Alfredsson L, Altshuler D, Gregersen PK, Klareskog L, Rioux JD. Plenge RM, et al. Among authors: klareskog l. Am J Hum Genet. 2005 Dec;77(6):1044-60. doi: 10.1086/498651. Epub 2005 Nov 1. Am J Hum Genet. 2005. PMID: 16380915 Free PMC article.
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.
Klareskog L, Stolt P, Lundberg K, Källberg H, Bengtsson C, Grunewald J, Rönnelid J, Harris HE, Ulfgren AK, Rantapää-Dahlqvist S, Eklund A, Padyukov L, Alfredsson L. Klareskog L, et al. Arthritis Rheum. 2006 Jan;54(1):38-46. doi: 10.1002/art.21575. Arthritis Rheum. 2006. PMID: 16385494 Free article.
735 results