Das R - Search Results

1

The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.

Selvaratnam R, VanSchouwen B, Fogolari F, Mazhab-Jafari MT, Das R, Melacini G. Selvaratnam R, et al. Among authors: das r. Biophys J. 2012 Feb 8;102(3):630-9. doi: 10.1016/j.bpj.2011.12.030. Epub 2012 Feb 7. Biophys J. 2012. PMID: 22325287 Free PMC article.

2

A model for agonism and antagonism in an ancient and ubiquitous cAMP-binding domain.

Das R, Melacini G. Das R, et al. J Biol Chem. 2007 Jan 5;282(1):581-93. doi: 10.1074/jbc.M607706200. Epub 2006 Oct 30. J Biol Chem. 2007. PMID: 17074757 Free article.

3

Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states.

Mazhab-Jafari MT, Das R, Fotheringham SA, SilDas S, Chowdhury S, Melacini G. Mazhab-Jafari MT, et al. Among authors: das r. J Am Chem Soc. 2007 Nov 21;129(46):14482-92. doi: 10.1021/ja0753703. Epub 2007 Oct 31. J Am Chem Soc. 2007. PMID: 17973384

4

Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP.

Das R, Mazhab-Jafari MT, Chowdhury S, SilDas S, Selvaratnam R, Melacini G. Das R, et al. J Biol Chem. 2008 Jul 11;283(28):19691-703. doi: 10.1074/jbc.M802164200. Epub 2008 Apr 14. J Biol Chem. 2008. PMID: 18411261 Free article.

5

Dynamically driven ligand selectivity in cyclic nucleotide binding domains.

Das R, Chowdhury S, Mazhab-Jafari MT, Sildas S, Selvaratnam R, Melacini G. Das R, et al. J Biol Chem. 2009 Aug 28;284(35):23682-96. doi: 10.1074/jbc.M109.011700. Epub 2009 Apr 29. J Biol Chem. 2009. PMID: 19403523 Free PMC article.

6

The auto-inhibitory role of the EPAC hinge helix as mapped by NMR.

Selvaratnam R, Mazhab-Jafari MT, Das R, Melacini G. Selvaratnam R, et al. Among authors: das r. PLoS One. 2012;7(11):e48707. doi: 10.1371/journal.pone.0048707. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185272 Free PMC article.

7

Mapping allostery through equilibrium perturbation NMR spectroscopy.

Das R, Abu-Abed M, Melacini G. Das R, et al. J Am Chem Soc. 2006 Jul 5;128(26):8406-7. doi: 10.1021/ja060046d. J Am Chem Soc. 2006. PMID: 16802799

8

NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit.

Esposito V, Sjoberg T, Das R, Brown S, Taylor SS, Melacini G. Esposito V, et al. Among authors: das r. J Biomol NMR. 2006;36 Suppl 1:64. doi: 10.1007/s10858-006-9050-9. Epub 2006 Oct 3. J Biomol NMR. 2006. PMID: 17016670 No abstract available.

9

Analysis and parametric optimization of 1H off-resonance relaxation NMR experiments designed to map polypeptide self-recognition and other noncovalent interactions.

Milojevic J, Esposito V, Das R, Melacini G. Milojevic J, et al. Among authors: das r. J Phys Chem B. 2006 Oct 19;110(41):20664-70. doi: 10.1021/jp063194z. J Phys Chem B. 2006. PMID: 17034257

10

cAMP activation of PKA defines an ancient signaling mechanism.

Das R, Esposito V, Abu-Abed M, Anand GS, Taylor SS, Melacini G. Das R, et al. Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):93-8. doi: 10.1073/pnas.0609033103. Epub 2006 Dec 20. Proc Natl Acad Sci U S A. 2007. PMID: 17182741 Free PMC article.

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