Mazhab-Jafari MT - Search Results

1

The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.

Selvaratnam R, VanSchouwen B, Fogolari F, Mazhab-Jafari MT, Das R, Melacini G. Selvaratnam R, et al. Biophys J. 2012 Feb 8;102(3):630-9. doi: 10.1016/j.bpj.2011.12.030. Epub 2012 Feb 7. Biophys J. 2012. PMID: 22325287 Free PMC article.

2

Unveiling the structural proteome of an Alzheimer's disease rat brain model.

Samani EK, Hasan SMN, Waas M, Keszei AFA, Xu X, Heydari M, Hill ME, McLaurin J, Kislinger T, Mazhab-Jafari MT. Samani EK, et al. Among authors: mazhab jafari mt. Structure. 2025 Jan 2;33(1):51-61.e3. doi: 10.1016/j.str.2024.11.004. Epub 2024 Nov 29. Structure. 2025. PMID: 39615488

3

Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex.

Nguyen DM, Rath DH, Devost D, Pétrin D, Rizk R, Ji AX, Narayanan N, Yong D, Zhai A, Kuntz DA, Mian MUQ, Pomroy NC, Keszei AFA, Benlekbir S, Mazhab-Jafari MT, Rubinstein JL, Hébert TE, Privé GG. Nguyen DM, et al. Among authors: mazhab jafari mt. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2315018121. doi: 10.1073/pnas.2315018121. Epub 2024 Apr 16. Proc Natl Acad Sci U S A. 2024. PMID: 38625940 Free PMC article.

4

Atomic model for core modifying region of human fatty acid synthase in complex with Denifanstat.

Hasan SMN, Lou JW, Keszei AFA, Dai DL, Mazhab-Jafari MT. Hasan SMN, et al. Among authors: mazhab jafari mt. Nat Commun. 2023 Jun 12;14(1):3460. doi: 10.1038/s41467-023-39266-y. Nat Commun. 2023. PMID: 37308485 Free PMC article.

5

FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation.

Barbulescu P, Chana CK, Wong MK, Ben Makhlouf I, Bruce JP, Feng Y, Keszei AFA, Wong C, Mohamad-Ramshan R, McGary LC, Kashem MA, Ceccarelli DF, Orlicky S, Fang Y, Kuang H, Mazhab-Jafari M, Pezo RC, Bhagwat AS, Pugh TJ, Gingras AC, Sicheri F, Martin A. Barbulescu P, et al. Nat Commun. 2024 Aug 30;15(1):7541. doi: 10.1038/s41467-024-52009-x. Nat Commun. 2024. PMID: 39215025 Free PMC article.

6

Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states.

Mazhab-Jafari MT, Das R, Fotheringham SA, SilDas S, Chowdhury S, Melacini G. Mazhab-Jafari MT, et al. J Am Chem Soc. 2007 Nov 21;129(46):14482-92. doi: 10.1021/ja0753703. Epub 2007 Oct 31. J Am Chem Soc. 2007. PMID: 17973384

7

Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP.

Das R, Mazhab-Jafari MT, Chowdhury S, SilDas S, Selvaratnam R, Melacini G. Das R, et al. J Biol Chem. 2008 Jul 11;283(28):19691-703. doi: 10.1074/jbc.M802164200. Epub 2008 Apr 14. J Biol Chem. 2008. PMID: 18411261 Free article.

8

Label-free assay for thermodynamic analysis of protein-ligand interactions: a multivariate strategy for allosteric ligand screening.

Gavina JM, Mazhab-Jafari MT, Melacini G, Britz-McKibbin P. Gavina JM, et al. Biochemistry. 2009 Jan 20;48(2):223-5. doi: 10.1021/bi802121g. Biochemistry. 2009. PMID: 19113833

9

Dynamically driven ligand selectivity in cyclic nucleotide binding domains.

Das R, Chowdhury S, Mazhab-Jafari MT, Sildas S, Selvaratnam R, Melacini G. Das R, et al. J Biol Chem. 2009 Aug 28;284(35):23682-96. doi: 10.1074/jbc.M109.011700. Epub 2009 Apr 29. J Biol Chem. 2009. PMID: 19403523 Free PMC article.

10

The auto-inhibitory role of the EPAC hinge helix as mapped by NMR.

Selvaratnam R, Mazhab-Jafari MT, Das R, Melacini G. Selvaratnam R, et al. PLoS One. 2012;7(11):e48707. doi: 10.1371/journal.pone.0048707. Epub 2012 Nov 21. PLoS One. 2012. PMID: 23185272 Free PMC article.

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