Tintori C - Search Results

1

Development of an AlphaScreen-based HIV-1 integrase dimerization assay for discovery of novel allosteric inhibitors.

Demeulemeester J, Tintori C, Botta M, Debyser Z, Christ F. Demeulemeester J, et al. Among authors: tintori c. J Biomol Screen. 2012 Jun;17(5):618-28. doi: 10.1177/1087057111436343. Epub 2012 Feb 14. J Biomol Screen. 2012. PMID: 22337657

2

Discovery of small molecule HIV-1 integrase dimerization inhibitors.

Tintori C, Demeulemeester J, Franchi L, Massa S, Debyser Z, Christ F, Botta M. Tintori C, et al. Bioorg Med Chem Lett. 2012 May 1;22(9):3109-14. doi: 10.1016/j.bmcl.2012.03.064. Epub 2012 Mar 21. Bioorg Med Chem Lett. 2012. PMID: 22483582

3

Kuwanon-L as a New Allosteric HIV-1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation.

Esposito F, Tintori C, Martini R, Christ F, Debyser Z, Ferrarese R, Cabiddu G, Corona A, Ceresola ER, Calcaterra A, Iovine V, Botta B, Clementi M, Canducci F, Botta M, Tramontano E. Esposito F, et al. Among authors: tintori c. Chembiochem. 2015 Nov;16(17):2507-12. doi: 10.1002/cbic.201500385. Epub 2015 Oct 26. Chembiochem. 2015. PMID: 26360521

4

Novel virtual screening protocol based on the combined use of molecular modeling and electron-ion interaction potential techniques to design HIV-1 integrase inhibitors.

Tintori C, Manetti F, Veljkovic N, Perovic V, Vercammen J, Hayes S, Massa S, Witvrouw M, Debyser Z, Veljkovic V, Botta M. Tintori C, et al. J Chem Inf Model. 2007 Jul-Aug;47(4):1536-44. doi: 10.1021/ci700078n. Epub 2007 Jul 3. J Chem Inf Model. 2007. PMID: 17608406

5

Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors.

Pasquini S, Mugnaini C, Tintori C, Botta M, Trejos A, Arvela RK, Larhed M, Witvrouw M, Michiels M, Christ F, Debyser Z, Corelli F. Pasquini S, et al. Among authors: tintori c. J Med Chem. 2008 Aug 28;51(16):5125-9. doi: 10.1021/jm8003784. Epub 2008 Jul 30. J Med Chem. 2008. PMID: 18665580

6

Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors.

Rajamaki S, Innitzer A, Falciani C, Tintori C, Christ F, Witvrouw M, Debyser Z, Massa S, Botta M. Rajamaki S, et al. Among authors: tintori c. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3615-8. doi: 10.1016/j.bmcl.2009.04.132. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19447621

7

A versatile and practical synthesis toward the development of novel HIV-1 integrase inhibitors.

Rinaldi M, Tintori C, Franchi L, Vignaroli G, Innitzer A, Massa S, Esté JA, Gonzalo E, Christ F, Debyser Z, Botta M. Rinaldi M, et al. Among authors: tintori c. ChemMedChem. 2011 Feb 7;6(2):343-52. doi: 10.1002/cmdc.201000510. Epub 2011 Jan 18. ChemMedChem. 2011. PMID: 21246739

8

Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies.

Mugnaini C, Rajamaki S, Tintori C, Corelli F, Massa S, Witvrouw M, Debyser Z, Veljkovic V, Botta M. Mugnaini C, et al. Among authors: tintori c. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5370-3. doi: 10.1016/j.bmcl.2007.08.005. Epub 2007 Aug 11. Bioorg Med Chem Lett. 2007. PMID: 17716893

9

Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments.

Tintori C, Esposito F, Morreale F, Martini R, Tramontano E, Botta M. Tintori C, et al. Bioorg Med Chem Lett. 2015 Aug 1;25(15):3013-6. doi: 10.1016/j.bmcl.2015.05.011. Epub 2015 May 15. Bioorg Med Chem Lett. 2015. PMID: 26048795

10

Targets looking for drugs: a multistep computational protocol for the development of structure-based pharmacophores and their applications for hit discovery.

Tintori C, Corradi V, Magnani M, Manetti F, Botta M. Tintori C, et al. J Chem Inf Model. 2008 Nov;48(11):2166-79. doi: 10.1021/ci800105p. J Chem Inf Model. 2008. PMID: 18942779

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