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477 results

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Page 1
Clonal selection drives genetic divergence of metastatic medulloblastoma.
Wu X, Northcott PA, Dubuc A, Dupuy AJ, Shih DJ, Witt H, Croul S, Bouffet E, Fults DW, Eberhart CG, Garzia L, Van Meter T, Zagzag D, Jabado N, Schwartzentruber J, Majewski J, Scheetz TE, Pfister SM, Korshunov A, Li XN, Scherer SW, Cho YJ, Akagi K, MacDonald TJ, Koster J, McCabe MG, Sarver AL, Collins VP, Weiss WA, Largaespada DA, Collier LS, Taylor MD. Wu X, et al. Among authors: witt h. Nature. 2012 Feb 15;482(7386):529-33. doi: 10.1038/nature10825. Nature. 2012. PMID: 22343890 Free PMC article.
The genetics of pediatric brain tumors.
Dubuc AM, Northcott PA, Mack S, Witt H, Pfister S, Taylor MD. Dubuc AM, et al. Among authors: witt h. Curr Neurol Neurosci Rep. 2010 May;10(3):215-23. doi: 10.1007/s11910-010-0103-9. Curr Neurol Neurosci Rep. 2010. PMID: 20425037 Review.
Medulloblastoma comprises four distinct molecular variants.
Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart CG, Mack S, Bouffet E, Clifford SC, Hawkins CE, French P, Rutka JT, Pfister S, Taylor MD. Northcott PA, et al. Among authors: witt h. J Clin Oncol. 2011 Apr 10;29(11):1408-14. doi: 10.1200/JCO.2009.27.4324. Epub 2010 Sep 7. J Clin Oncol. 2011. PMID: 20823417 Free PMC article.
Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma.
Traenka C, Remke M, Korshunov A, Bender S, Hielscher T, Northcott PA, Witt H, Ryzhova M, Felsberg J, Benner A, Riester S, Scheurlen W, Grunewald TG, von Deimling A, Kulozik AE, Reifenberger G, Taylor MD, Lichter P, Butt E, Pfister SM. Traenka C, et al. Among authors: witt h. Cancer Res. 2010 Oct 15;70(20):8003-14. doi: 10.1158/0008-5472.CAN-10-0592. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924110
TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.
Pfaff E, Remke M, Sturm D, Benner A, Witt H, Milde T, von Bueren AO, Wittmann A, Schöttler A, Jorch N, Graf N, Kulozik AE, Witt O, Scheurlen W, von Deimling A, Rutkowski S, Taylor MD, Tabori U, Lichter P, Korshunov A, Pfister SM. Pfaff E, et al. Among authors: witt h, witt o. J Clin Oncol. 2010 Dec 10;28(35):5188-96. doi: 10.1200/JCO.2010.31.1670. Epub 2010 Nov 8. J Clin Oncol. 2010. PMID: 21060032
Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas.
Jacob K, Quang-Khuong DA, Jones DT, Witt H, Lambert S, Albrecht S, Witt O, Vezina C, Shirinian M, Faury D, Garami M, Hauser P, Klekner A, Bognar L, Farmer JP, Montes JL, Atkinson J, Hawkins C, Korshunov A, Collins VP, Pfister SM, Tabori U, Jabado N. Jacob K, et al. Among authors: witt h, witt o. Clin Cancer Res. 2011 Jul 15;17(14):4650-60. doi: 10.1158/1078-0432.CCR-11-0127. Epub 2011 May 24. Clin Cancer Res. 2011. PMID: 21610151
Adult medulloblastoma comprises three major molecular variants.
Remke M, Hielscher T, Northcott PA, Witt H, Ryzhova M, Wittmann A, Benner A, von Deimling A, Scheurlen W, Perry A, Croul S, Kulozik AE, Lichter P, Taylor MD, Pfister SM, Korshunov A. Remke M, et al. Among authors: witt h. J Clin Oncol. 2011 Jul 1;29(19):2717-23. doi: 10.1200/JCO.2011.34.9373. Epub 2011 May 31. J Clin Oncol. 2011. PMID: 21632505
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.
Witt H, Mack SC, Ryzhova M, Bender S, Sill M, Isserlin R, Benner A, Hielscher T, Milde T, Remke M, Jones DT, Northcott PA, Garzia L, Bertrand KC, Wittmann A, Yao Y, Roberts SS, Massimi L, Van Meter T, Weiss WA, Gupta N, Grajkowska W, Lach B, Cho YJ, von Deimling A, Kulozik AE, Witt O, Bader GD, Hawkins CE, Tabori U, Guha A, Rutka JT, Lichter P, Korshunov A, Taylor MD, Pfister SM. Witt H, et al. Among authors: witt o. Cancer Cell. 2011 Aug 16;20(2):143-57. doi: 10.1016/j.ccr.2011.07.007. Cancer Cell. 2011. PMID: 21840481 Free PMC article.
FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma.
Remke M, Hielscher T, Korshunov A, Northcott PA, Bender S, Kool M, Westermann F, Benner A, Cin H, Ryzhova M, Sturm D, Witt H, Haag D, Toedt G, Wittmann A, Schöttler A, von Bueren AO, von Deimling A, Rutkowski S, Scheurlen W, Kulozik AE, Taylor MD, Lichter P, Pfister SM. Remke M, et al. Among authors: witt h. J Clin Oncol. 2011 Oct 10;29(29):3852-61. doi: 10.1200/JCO.2011.36.2798. Epub 2011 Sep 12. J Clin Oncol. 2011. PMID: 21911727
477 results