Pothoulakis C - Search Results

1

Clostridial toxins: sensing a target in a hostile gut environment.

Oezguen N, Power TD, Urvil P, Feng H, Pothoulakis C, Stamler JS, Braun W, Savidge TC. Oezguen N, et al. Among authors: pothoulakis c. Gut Microbes. 2012 Jan-Feb;3(1):35-41. doi: 10.4161/gmic.19250. Epub 2012 Jan 1. Gut Microbes. 2012. PMID: 22356854 Free PMC article. Review.

2

Clostridium difficile toxin B is an inflammatory enterotoxin in human intestine.

Savidge TC, Pan WH, Newman P, O'brien M, Anton PM, Pothoulakis C. Savidge TC, et al. Among authors: pothoulakis c. Gastroenterology. 2003 Aug;125(2):413-20. doi: 10.1016/s0016-5085(03)00902-8. Gastroenterology. 2003. PMID: 12891543

3

Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK.

Kim H, Rhee SH, Kokkotou E, Na X, Savidge T, Moyer MP, Pothoulakis C, LaMont JT. Kim H, et al. Among authors: pothoulakis c. J Biol Chem. 2005 Jun 3;280(22):21237-45. doi: 10.1074/jbc.M413842200. Epub 2005 Mar 14. J Biol Chem. 2005. PMID: 15767259 Free article.

4

Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione.

Savidge TC, Newman P, Pothoulakis C, Ruhl A, Neunlist M, Bourreille A, Hurst R, Sofroniew MV. Savidge TC, et al. Among authors: pothoulakis c. Gastroenterology. 2007 Apr;132(4):1344-58. doi: 10.1053/j.gastro.2007.01.051. Epub 2007 Feb 1. Gastroenterology. 2007. PMID: 17408650

5

Urocortin II mediates pro-inflammatory effects in human colonocytes via corticotropin-releasing hormone receptor 2alpha.

Moss AC, Anton P, Savidge T, Newman P, Cheifetz AS, Gay J, Paraschos S, Winter MW, Moyer MP, Karalis K, Kokkotou E, Pothoulakis C. Moss AC, et al. Among authors: pothoulakis c. Gut. 2007 Sep;56(9):1210-7. doi: 10.1136/gut.2006.110668. Epub 2007 Apr 5. Gut. 2007. PMID: 17412781 Free PMC article.

6

Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice.

Kokkotou E, Espinoza DO, Torres D, Karagiannides I, Kosteletos S, Savidge T, O'Brien M, Pothoulakis C. Kokkotou E, et al. Among authors: pothoulakis c. Gut. 2009 Jan;58(1):34-40. doi: 10.1136/gut.2008.155341. Epub 2008 Sep 29. Gut. 2009. PMID: 18824554 Free PMC article.

7

Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins.

Savidge TC, Urvil P, Oezguen N, Ali K, Choudhury A, Acharya V, Pinchuk I, Torres AG, English RD, Wiktorowicz JE, Loeffelholz M, Kumar R, Shi L, Nie W, Braun W, Herman B, Hausladen A, Feng H, Stamler JS, Pothoulakis C. Savidge TC, et al. Among authors: pothoulakis c. Nat Med. 2011 Aug 21;17(9):1136-41. doi: 10.1038/nm.2405. Nat Med. 2011. PMID: 21857653 Free PMC article.

8

Therapeutic Mechanism of Macrophage Inflammatory Protein 1 α Neutralizing Antibody (CCL3) in Clostridium difficile Infection in Mice.

Wang J, Ortiz C, Fontenot L, Mukhopadhyay R, Xie Y, Chen X, Feng H, Pothoulakis C, Koon HW. Wang J, et al. Among authors: pothoulakis c. J Infect Dis. 2020 Apr 27;221(10):1623-1635. doi: 10.1093/infdis/jiz640. J Infect Dis. 2020. PMID: 31793629 Free PMC article.

9

Intravenous immunoglobulin therapy for severe Clostridium difficile colitis.

Salcedo J, Keates S, Pothoulakis C, Warny M, Castagliuolo I, LaMont JT, Kelly CP. Salcedo J, et al. Among authors: pothoulakis c. Gut. 1997 Sep;41(3):366-70. doi: 10.1136/gut.41.3.366. Gut. 1997. PMID: 9378393 Free PMC article.

10

Bovine immunoglobulin concentrate-clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine.

Warny M, Fatimi A, Bostwick EF, Laine DC, Lebel F, LaMont JT, Pothoulakis C, Kelly CP. Warny M, et al. Among authors: pothoulakis c. Gut. 1999 Feb;44(2):212-7. doi: 10.1136/gut.44.2.212. Gut. 1999. PMID: 9895380 Free PMC article. Clinical Trial.

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