Akopian TN - Search Results

1

Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection.

Raju RM, Unnikrishnan M, Rubin DH, Krishnamoorthy V, Kandror O, Akopian TN, Goldberg AL, Rubin EJ. Raju RM, et al. Among authors: akopian tn. PLoS Pathog. 2012 Feb;8(2):e1002511. doi: 10.1371/journal.ppat.1002511. Epub 2012 Feb 16. PLoS Pathog. 2012. PMID: 22359499 Free PMC article.

2

Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum.

Akopian TN, Kisselev AF, Goldberg AL. Akopian TN, et al. J Biol Chem. 1997 Jan 17;272(3):1791-8. doi: 10.1074/jbc.272.3.1791. J Biol Chem. 1997. PMID: 8999862 Free article.

3

Lactacystin and clasto-lactacystin beta-lactone modify multiple proteasome beta-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I antigen presentation.

Craiu A, Gaczynska M, Akopian T, Gramm CF, Fenteany G, Goldberg AL, Rock KL. Craiu A, et al. J Biol Chem. 1997 May 16;272(20):13437-45. doi: 10.1074/jbc.272.20.13437. J Biol Chem. 1997. PMID: 9148969 Free article.

4

New insights into the mechanisms and importance of the proteasome in intracellular protein degradation.

Goldberg AL, Akopian TN, Kisselev AF, Lee DH, Rohrwild M. Goldberg AL, et al. Among authors: akopian tn. Biol Chem. 1997 Mar-Apr;378(3-4):131-40. Biol Chem. 1997. PMID: 9165063 Review.

5

Protein degradation by the proteasome and dissection of its in vivo importance with synthetic inhibitors.

Goldberg AL, Akopian TN, Kisselev AF, Lee DH. Goldberg AL, et al. Among authors: akopian tn. Mol Biol Rep. 1997 Mar;24(1-2):69-75. doi: 10.1023/a:1006860828265. Mol Biol Rep. 1997. PMID: 9228284 Review. No abstract available.

6

Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide.

Craiu A, Akopian T, Goldberg A, Rock KL. Craiu A, et al. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10850-5. doi: 10.1073/pnas.94.20.10850. Proc Natl Acad Sci U S A. 1997. PMID: 9380723 Free PMC article.

7

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes.

Kisselev AF, Akopian TN, Goldberg AL. Kisselev AF, et al. Among authors: akopian tn. J Biol Chem. 1998 Jan 23;273(4):1982-9. doi: 10.1074/jbc.273.4.1982. J Biol Chem. 1998. PMID: 9442034 Free article.

8

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation.

Kisselev AF, Akopian TN, Woo KM, Goldberg AL. Kisselev AF, et al. Among authors: akopian tn. J Biol Chem. 1999 Feb 5;274(6):3363-71. doi: 10.1074/jbc.274.6.3363. J Biol Chem. 1999. PMID: 9920878 Free article.

9

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown.

Kisselev AF, Akopian TN, Castillo V, Goldberg AL. Kisselev AF, et al. Among authors: akopian tn. Mol Cell. 1999 Sep;4(3):395-402. doi: 10.1016/s1097-2765(00)80341-x. Mol Cell. 1999. PMID: 10518220 Free article.

10

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase.

Saric T, Beninga J, Graef CI, Akopian TN, Rock KL, Goldberg AL. Saric T, et al. Among authors: akopian tn. J Biol Chem. 2001 Sep 28;276(39):36474-81. doi: 10.1074/jbc.M105517200. Epub 2001 Jul 30. J Biol Chem. 2001. PMID: 11479311 Free article.

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