Hughes SH - Search Results

1

Multiple sources of contamination in samples from patients reported to have XMRV infection.

Kearney MF, Spindler J, Wiegand A, Shao W, Anderson EM, Maldarelli F, Ruscetti FW, Mellors JW, Hughes SH, Le Grice SF, Coffin JM. Kearney MF, et al. Among authors: hughes sh. PLoS One. 2012;7(2):e30889. doi: 10.1371/journal.pone.0030889. Epub 2012 Feb 20. PLoS One. 2012. PMID: 22363509 Free PMC article.

2

Redesignation of the RNase D activity associated with retroviral reverse transcriptase as RNase H.

Hostomsky Z, Hughes SH, Goff SP, Le Grice SF. Hostomsky Z, et al. Among authors: hughes sh. J Virol. 1994 Mar;68(3):1970-1. doi: 10.1128/JVI.68.3.1970-1971.1994. J Virol. 1994. PMID: 7509004 Free PMC article.

3

What is the orientation of DNA polymerases on their templates?

Hughes SH, Hostomsky Z, Le Grice SF, Lentz K, Arnold E. Hughes SH, et al. J Virol. 1996 May;70(5):2679-83. doi: 10.1128/JVI.70.5.2679-2683.1996. J Virol. 1996. PMID: 8627740 Free PMC article. Review. No abstract available.

4

Altering the RNase H primer grip of human immunodeficiency virus reverse transcriptase modifies cleavage specificity.

Rausch JW, Lener D, Miller JT, Julias JG, Hughes SH, Le Grice SF. Rausch JW, et al. Among authors: hughes sh. Biochemistry. 2002 Apr 16;41(15):4856-65. doi: 10.1021/bi015970t. Biochemistry. 2002. PMID: 11939780

5

In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques.

Ambrose Z, Boltz V, Palmer S, Coffin JM, Hughes SH, Kewalramani VN. Ambrose Z, et al. Among authors: hughes sh. J Virol. 2004 Dec;78(24):13553-61. doi: 10.1128/JVI.78.24.13553-13561.2004. J Virol. 2004. PMID: 15564466 Free PMC article.

6

HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision.

Delviks-Frankenberry KA, Nikolenko GN, Boyer PL, Hughes SH, Coffin JM, Jere A, Pathak VK. Delviks-Frankenberry KA, et al. Among authors: hughes sh. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10943-8. doi: 10.1073/pnas.0804660105. Epub 2008 Jul 30. Proc Natl Acad Sci U S A. 2008. PMID: 18667707 Free PMC article.

7

Flexible use of nuclear import pathways by HIV-1.

Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman DR, Coffin JM, Hughes SH, Unutmaz D, Engelman A, KewalRamani VN. Lee K, et al. Among authors: hughes sh. Cell Host Microbe. 2010 Mar 18;7(3):221-33. doi: 10.1016/j.chom.2010.02.007. Cell Host Microbe. 2010. PMID: 20227665 Free PMC article.

8

Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication.

Abram ME, Ferris AL, Shao W, Alvord WG, Hughes SH. Abram ME, et al. Among authors: hughes sh. J Virol. 2010 Oct;84(19):9864-78. doi: 10.1128/JVI.00915-10. Epub 2010 Jul 21. J Virol. 2010. PMID: 20660205 Free PMC article.

9

Mutagenesis of human immunodeficiency virus reverse transcriptase p51 subunit defines residues contributing to vinylogous urea inhibition of ribonuclease H activity.

Chung S, Miller JT, Johnson BC, Hughes SH, Le Grice SF. Chung S, et al. Among authors: hughes sh. J Biol Chem. 2012 Feb 3;287(6):4066-75. doi: 10.1074/jbc.M111.314781. Epub 2011 Nov 21. J Biol Chem. 2012. PMID: 22105069 Free PMC article.

10

False-positive HIV PCR test following ex vivo lentiviral gene transfer treatment of X-linked severe combined immunodeficiency vector.

De Ravin SS, Gray JT, Throm RE, Spindler J, Kearney M, Wu X, Coffin JM, Hughes SH, Malderelli F, Sorrentino BP, Malech HL. De Ravin SS, et al. Among authors: hughes sh. Mol Ther. 2014 Feb;22(2):244-245. doi: 10.1038/mt.2013.296. Mol Ther. 2014. PMID: 24487563 Free PMC article. No abstract available.

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