Hsieh AC - Search Results

1

The translational landscape of mTOR signalling steers cancer initiation and metastasis.

Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, Weissman JS, Shokat KM, Rommel C, Ruggero D. Hsieh AC, et al. Nature. 2012 Feb 22;485(7396):55-61. doi: 10.1038/nature10912. Nature. 2012. PMID: 22367541 Free PMC article.

2

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E.

Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, Meyuhas O, Shokat KM, Ruggero D. Hsieh AC, et al. Cancer Cell. 2010 Mar 16;17(3):249-61. doi: 10.1016/j.ccr.2010.01.021. Cancer Cell. 2010. PMID: 20227039 Free PMC article.

3

Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer.

Hsieh AC, Ruggero D. Hsieh AC, et al. Clin Cancer Res. 2010 Oct 15;16(20):4914-20. doi: 10.1158/1078-0432.CCR-10-0433. Epub 2010 Aug 11. Clin Cancer Res. 2010. PMID: 20702611 Free PMC article.

4

Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.

Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Ishijima J, Shiroishi T, Barna M. Kondrashov N, et al. Among authors: hsieh ac. Cell. 2011 Apr 29;145(3):383-397. doi: 10.1016/j.cell.2011.03.028. Cell. 2011. PMID: 21529712 Free PMC article.

5

Assessing gene-level translational control from ribosome profiling.

Olshen AB, Hsieh AC, Stumpf CR, Olshen RA, Ruggero D, Taylor BS. Olshen AB, et al. Among authors: hsieh ac. Bioinformatics. 2013 Dec 1;29(23):2995-3002. doi: 10.1093/bioinformatics/btt533. Epub 2013 Sep 18. Bioinformatics. 2013. PMID: 24048356 Free PMC article.

6

PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance.

Edlind MP, Hsieh AC. Edlind MP, et al. Among authors: hsieh ac. Asian J Androl. 2014 May-Jun;16(3):378-86. doi: 10.4103/1008-682X.122876. Asian J Androl. 2014. PMID: 24759575 Free PMC article. Review.

7

YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence.

Sheridan CM, Grogan TR, Nguyen HG, Galet C, Rettig MB, Hsieh AC, Ruggero D. Sheridan CM, et al. Among authors: hsieh ac. Oncotarget. 2015 Apr 10;6(10):7470-80. doi: 10.18632/oncotarget.3477. Oncotarget. 2015. PMID: 25797255 Free PMC article.

8

Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors.

Hsieh AC, Nguyen HG, Wen L, Edlind MP, Carroll PR, Kim W, Ruggero D. Hsieh AC, et al. Sci Signal. 2015 Nov 17;8(403):ra116. doi: 10.1126/scisignal.aad5111. Sci Signal. 2015. PMID: 26577921 Free PMC article.

9

Development of a stress response therapy targeting aggressive prostate cancer.

Nguyen HG, Conn CS, Kye Y, Xue L, Forester CM, Cowan JE, Hsieh AC, Cunningham JT, Truillet C, Tameire F, Evans MJ, Evans CP, Yang JC, Hann B, Koumenis C, Walter P, Carroll PR, Ruggero D. Nguyen HG, et al. Among authors: hsieh ac. Sci Transl Med. 2018 May 2;10(439):eaar2036. doi: 10.1126/scitranslmed.aar2036. Sci Transl Med. 2018. PMID: 29720449 Free PMC article.

10

Multiplexed functional genomic analysis of 5' untranslated region mutations across the spectrum of prostate cancer.

Lim Y, Arora S, Schuster SL, Corey L, Fitzgibbon M, Wladyka CL, Wu X, Coleman IM, Delrow JJ, Corey E, True LD, Nelson PS, Ha G, Hsieh AC. Lim Y, et al. Among authors: hsieh ac. Nat Commun. 2021 Jul 9;12(1):4217. doi: 10.1038/s41467-021-24445-6. Nat Commun. 2021. PMID: 34244513 Free PMC article.

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