Al Safarjalani ON - Search Results

1

Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.

Al Safarjalani ON, Rais R, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2012 Jun;69(6):1449-55. doi: 10.1007/s00280-012-1842-x. Epub 2012 Feb 29. Cancer Chemother Pharmacol. 2012. PMID: 22373605

2

5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens.

Al Safarjalani ON, Zhou XJ, Rais RH, Shi J, Schinazi RF, Naguib FN, El Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2005 Jun;55(6):541-51. doi: 10.1007/s00280-004-0967-y. Epub 2005 Feb 24. Cancer Chemother Pharmacol. 2005. PMID: 15729584

3

Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor.

Al Safarjalani ON, Rais R, Shi J, Schinazi RF, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2006 Nov;58(5):692-8. doi: 10.1007/s00280-006-0213-x. Epub 2006 Mar 10. Cancer Chemother Pharmacol. 2006. PMID: 16528530

4

Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: biological activities and selective toxicities.

Al Safarjalani ON, Rais RH, Kim YA, Chu CK, Naguib FN, El Kouni MH. Al Safarjalani ON, et al. Biochem Pharmacol. 2010 Oct 1;80(7):955-63. doi: 10.1016/j.bcp.2010.06.001. Epub 2010 Jun 10. Biochem Pharmacol. 2010. PMID: 20541538 Free PMC article.

5

Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy.

Ashour OM, Al Safarjalani ON, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: al safarjalani on. Cancer Chemother Pharmacol. 2000;45(5):351-61. doi: 10.1007/s002800051002. Cancer Chemother Pharmacol. 2000. PMID: 10803917

6

Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2',3',5'-tri-O-acetyluridine, a prodrug of uridine.

Ashour OM, Naguib FN, Panzica RP, Al Safarjalani ON, el Kouni MH. Ashour OM, et al. Among authors: al safarjalani on. Biochem Pharmacol. 2000 Aug 1;60(3):427-31. doi: 10.1016/s0006-2952(00)00342-7. Biochem Pharmacol. 2000. PMID: 10856438

7

5-phenylthioacyclouridine: a potent and specific inhibitor of uridine phosphorylase.

el Kouni MH, Goudgaon NM, Rafeeq M, Al Safarjalani ON, Schinazi RF, Naguib FN. el Kouni MH, et al. Among authors: al safarjalani on. Biochem Pharmacol. 2000 Sep 15;60(6):851-6. doi: 10.1016/s0006-2952(00)00410-x. Biochem Pharmacol. 2000. PMID: 10930540

8

Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy.

Al Safarjalani ON, Zhou XJ, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2001 Aug;48(2):145-50. doi: 10.1007/s002800100292. Cancer Chemother Pharmacol. 2001. PMID: 11565561

9

Enhancement of the bioavailability of oral uridine by coadministration of 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for uridine rescue regimens in chemotherapy.

Al Safarjalani ON, Zhou XJ, Naguib FN, Shi J, Schinazi RF, el Kouni MH. Al Safarjalani ON, et al. Cancer Chemother Pharmacol. 2001 Nov;48(5):389-97. doi: 10.1007/s002800100353. Cancer Chemother Pharmacol. 2001. PMID: 11761457

10

Uptake of nitrobenzylthioinosine and purine beta-L-nucleosides by intracellular Toxoplasma gondii.

Al Safarjalani ON, Naguib FN, El Kouni MH. Al Safarjalani ON, et al. Antimicrob Agents Chemother. 2003 Oct;47(10):3247-51. doi: 10.1128/AAC.47.10.3247-3251.2003. Antimicrob Agents Chemother. 2003. PMID: 14506037 Free PMC article.

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