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Conditionally immortalized mouse embryonic fibroblasts retain proliferative activity without compromising multipotent differentiation potential.
Huang E, Bi Y, Jiang W, Luo X, Yang K, Gao JL, Gao Y, Luo Q, Shi Q, Kim SH, Liu X, Li M, Hu N, Liu H, Cui J, Zhang W, Li R, Chen X, Shen J, Kong Y, Zhang J, Wang J, Luo J, He BC, Wang H, Reid RR, Luu HH, Haydon RC, Yang L, He TC. Huang E, et al. Among authors: chen x. PLoS One. 2012;7(2):e32428. doi: 10.1371/journal.pone.0032428. Epub 2012 Feb 23. PLoS One. 2012. PMID: 22384246 Free PMC article.
Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells.
Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, Zhang H, Li R, Kong Y, Chen X, Shui W, Wang N, Zhao C, Wu N, He Y, Nan G, Chen X, Wen S, Zhang H, Deng F, Wan L, Luu HH, Haydon RC, Shi LL, He TC, Shi Q. Zhang J, et al. Among authors: chen x. PLoS One. 2013 Sep 3;8(9):e73086. doi: 10.1371/journal.pone.0073086. eCollection 2013. PLoS One. 2013. PMID: 24019898 Free PMC article.
The piggyBac transposon-mediated expression of SV40 T antigen efficiently immortalizes mouse embryonic fibroblasts (MEFs).
Wang N, Zhang W, Cui J, Zhang H, Chen X, Li R, Wu N, Chen X, Wen S, Zhang J, Yin L, Deng F, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Ye J, Deng Y, Wang Z, Qiao M, Luu HH, Haydon RC, Shi LL, Liang H, He TC. Wang N, et al. Among authors: chen x. PLoS One. 2014 May 20;9(5):e97316. doi: 10.1371/journal.pone.0097316. eCollection 2014. PLoS One. 2014. PMID: 24845466 Free PMC article.
Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells.
Huang E, Zhu G, Jiang W, Yang K, Gao Y, Luo Q, Gao JL, Kim SH, Liu X, Li M, Shi Q, Hu N, Wang L, Liu H, Cui J, Zhang W, Li R, Chen X, Kong YH, Zhang J, Wang J, Shen J, Bi Y, Statz J, He BC, Luo J, Wang H, Xiong F, Luu HH, Haydon RC, Yang L, He TC. Huang E, et al. Among authors: chen x. J Bone Miner Res. 2012 Jul;27(7):1566-75. doi: 10.1002/jbmr.1622. J Bone Miner Res. 2012. PMID: 22467218 Free article.
BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells.
Hu N, Jiang D, Huang E, Liu X, Li R, Liang X, Kim SH, Chen X, Gao JL, Zhang H, Zhang W, Kong YH, Zhang J, Wang J, Shui W, Luo X, Liu B, Cui J, Rogers MR, Shen J, Zhao C, Wang N, Wu N, Luu HH, Haydon RC, He TC, Huang W. Hu N, et al. Among authors: chen x. J Cell Sci. 2013 Jan 15;126(Pt 2):532-41. doi: 10.1242/jcs.114231. Epub 2012 Nov 30. J Cell Sci. 2013. PMID: 23203800 Free PMC article.
Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells.
Liu X, Qin J, Luo Q, Bi Y, Zhu G, Jiang W, Kim SH, Li M, Su Y, Nan G, Cui J, Zhang W, Li R, Chen X, Kong Y, Zhang J, Wang J, Rogers MR, Zhang H, Shui W, Zhao C, Wang N, Liang X, Wu N, He Y, Luu HH, Haydon RC, Shi LL, Li T, He TC, Li M. Liu X, et al. Among authors: chen x. J Cell Mol Med. 2013 Sep;17(9):1160-72. doi: 10.1111/jcmm.12097. Epub 2013 Jul 11. J Cell Mol Med. 2013. PMID: 23844832 Free PMC article.
A simplified and versatile system for the simultaneous expression of multiple siRNAs in mammalian cells using Gibson DNA Assembly.
Deng F, Chen X, Liao Z, Yan Z, Wang Z, Deng Y, Zhang Q, Zhang Z, Ye J, Qiao M, Li R, Denduluri S, Wang J, Wei Q, Li M, Geng N, Zhao L, Zhou G, Zhang P, Luu HH, Haydon RC, Reid RR, Yang T, He TC. Deng F, et al. Among authors: chen x. PLoS One. 2014 Nov 14;9(11):e113064. doi: 10.1371/journal.pone.0113064. eCollection 2014. PLoS One. 2014. PMID: 25398142 Free PMC article.
Conditional immortalization establishes a repertoire of mouse melanocyte progenitors with distinct melanogenic differentiation potential.
Yang K, Chen J, Jiang W, Huang E, Cui J, Kim SH, Hu N, Liu H, Zhang W, Li R, Chen X, Kong Y, Zhang J, Wang J, Wang L, Shen J, Luu HH, Haydon RC, Lian X, Yang T, He TC. Yang K, et al. Among authors: chen j, chen x. J Invest Dermatol. 2012 Oct;132(10):2479-2483. doi: 10.1038/jid.2012.145. Epub 2012 May 17. J Invest Dermatol. 2012. PMID: 22592154 Free PMC article. No abstract available.
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