Wheate NJ - Search Results

1

Cisplatin-tethered gold nanoparticles that exhibit enhanced reproducibility, drug loading, and stability: a step closer to pharmaceutical approval?

Craig GE, Brown SD, Lamprou DA, Graham D, Wheate NJ. Craig GE, et al. Among authors: wheate nj. Inorg Chem. 2012 Mar 19;51(6):3490-7. doi: 10.1021/ic202197g. Epub 2012 Mar 5. Inorg Chem. 2012. PMID: 22390791 Free article.

2

Improving platinum(II)-based anticancer drug delivery using cucurbit[n]urils.

Wheate NJ. Wheate NJ. J Inorg Biochem. 2008 Dec;102(12):2060-6. doi: 10.1016/j.jinorgbio.2008.06.005. Epub 2008 Jun 20. J Inorg Biochem. 2008. PMID: 18653238 Review.

3

Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2mu-dpzm]2+ and its implications for anticancer drug delivery.

Wheate NJ, Abbott GM, Tate RJ, Clements CJ, Edrada-Ebel R, Johnston BF. Wheate NJ, et al. J Inorg Biochem. 2009 Mar;103(3):448-54. doi: 10.1016/j.jinorgbio.2008.12.011. Epub 2008 Dec 27. J Inorg Biochem. 2009. PMID: 19171382

4

Gold nanoparticles for the improved anticancer drug delivery of the active component of oxaliplatin.

Brown SD, Nativo P, Smith JA, Stirling D, Edwards PR, Venugopal B, Flint DJ, Plumb JA, Graham D, Wheate NJ. Brown SD, et al. Among authors: wheate nj. J Am Chem Soc. 2010 Apr 7;132(13):4678-84. doi: 10.1021/ja908117a. J Am Chem Soc. 2010. PMID: 20225865 Free PMC article.

5

The status of platinum anticancer drugs in the clinic and in clinical trials.

Wheate NJ, Walker S, Craig GE, Oun R. Wheate NJ, et al. Dalton Trans. 2010 Sep 21;39(35):8113-27. doi: 10.1039/c0dt00292e. Epub 2010 Jun 30. Dalton Trans. 2010. PMID: 20593091

6

Evaluation of anionic half generation 3.5-6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin.

Kirkpatrick GJ, Plumb JA, Sutcliffe OB, Flint DJ, Wheate NJ. Kirkpatrick GJ, et al. Among authors: wheate nj. J Inorg Biochem. 2011 Sep;105(9):1115-22. doi: 10.1016/j.jinorgbio.2011.05.017. Epub 2011 May 27. J Inorg Biochem. 2011. PMID: 21704583

7

Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity.

Brown SD, Trotter KD, Sutcliffe OB, Plumb JA, Waddell B, Briggs NE, Wheate NJ. Brown SD, et al. Among authors: wheate nj. Dalton Trans. 2012 Oct 7;41(37):11330-9. doi: 10.1039/c2dt31313h. Epub 2012 Aug 10. Dalton Trans. 2012. PMID: 22886151

8

A cisplatin slow-release hydrogel drug delivery system based on a formulation of the macrocycle cucurbit[7]uril, gelatin and polyvinyl alcohol.

Oun R, Plumb JA, Wheate NJ. Oun R, et al. Among authors: wheate nj. J Inorg Biochem. 2014 May;134:100-5. doi: 10.1016/j.jinorgbio.2014.02.004. Epub 2014 Feb 18. J Inorg Biochem. 2014. PMID: 24595010

9

Amide coupling reaction for the synthesis of bispyridine-based ligands and their complexation to platinum as dinuclear anticancer agents.

Apps MG, Johnson BW, Sutcliffe OB, Brown SD, Wheate NJ. Apps MG, et al. Among authors: wheate nj. J Vis Exp. 2014 May 28;(87):51740. doi: 10.3791/51740. J Vis Exp. 2014. PMID: 24893964 Free PMC article.

10

Polyamide platinum anticancer complexes designed to target specific DNA sequences.

Jaramillo D, Wheate NJ, Ralph SF, Howard WA, Tor Y, Aldrich-Wright JR. Jaramillo D, et al. Among authors: wheate nj. Inorg Chem. 2006 Jul 24;45(15):6004-13. doi: 10.1021/ic060383n. Inorg Chem. 2006. PMID: 16842007

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