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Induced pluripotent stem cell-based Drug Repurposing for Amyotrophic lateral sclerosis Medicine (iDReAM) study: protocol for a phase I dose escalation study of bosutinib for amyotrophic lateral sclerosis patients.
Imamura K, Izumi Y, Banno H, Uozumi R, Morita S, Egawa N, Ayaki T, Nagai M, Nishiyama K, Watanabe Y, Hanajima R, Oki R, Fujita K, Takahashi N, Ikeda T, Shimizu A, Morinaga A, Hirohashi T, Fujii Y, Takahashi R, Inoue H. Imamura K, et al. Among authors: hirohashi t. BMJ Open. 2019 Dec 2;9(12):e033131. doi: 10.1136/bmjopen-2019-033131. BMJ Open. 2019. PMID: 31796494 Free PMC article.
Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial.
Imamura K, Izumi Y, Nagai M, Nishiyama K, Watanabe Y, Hanajima R, Egawa N, Ayaki T, Oki R, Fujita K, Uozumi R, Morinaga A, Hirohashi T, Fujii Y, Yamamoto T, Tatebe H, Tokuda T, Takahashi N, Morita S, Takahashi R, Inoue H. Imamura K, et al. Among authors: hirohashi t. EClinicalMedicine. 2022 Oct 25;53:101707. doi: 10.1016/j.eclinm.2022.101707. eCollection 2022 Nov. EClinicalMedicine. 2022. PMID: 36467452 Free PMC article.
Pharmacokinetics, safety, and efficacy of an alternative dosing regimen of sasanlimab in participants with advanced NSCLC and other malignancies.
Penkov K, Bondarenko I, Saenko DV, Kulyaba Y, Guo J, Gong Y, Yamamoto N, Hotko YS, Boyko V, Fadeeva NV, Ursol GM, Ahn HK, Kislov NV, Shen CI, Davis C, Kowalski K, Michelon E, Pavlov D, Hirohashi T, Cho BC. Penkov K, et al. Among authors: hirohashi t. Ther Adv Med Oncol. 2024 Sep 11;16:17588359241274592. doi: 10.1177/17588359241274592. eCollection 2024. Ther Adv Med Oncol. 2024. PMID: 39281971 Free PMC article.
Fluid retention and weight loss in refractory cancer cachexia.
Amano K, Okamura S, Baracos V, Mori N, Sakaguchi T, Uneno Y, Hiratsuka Y, Hamano J, Miura T, Ishiki H, Yokomichi N, Hatano Y, Morita T, Mori M; East-Asian collaborative cross-cultural Study to Elucidate the Dying process (EASED) investigators. Amano K, et al. BMJ Support Palliat Care. 2024 Feb 23:spcare-2024-004820. doi: 10.1136/spcare-2024-004820. Online ahead of print. BMJ Support Palliat Care. 2024. PMID: 38395597
Identification and mechanistic investigation of ellagitannins from Osbeckia octandra that attenuate liver fibrosis via the TGF-β/SMAD signaling pathway.
Bogahawaththa S, Kawamura T, Bandaranayake U, Hirakawa T, Yamada G, Ishino H, Hirohashi T, Kawaguchi SI, Wijesundera KK, Wijayagunawardane MPB, Ishimaru K, Kodithuwakku SP, Tsujita T. Bogahawaththa S, et al. Among authors: hirohashi t. Biosci Biotechnol Biochem. 2023 Oct 25;87(11):1295-1309. doi: 10.1093/bbb/zbad114. Biosci Biotechnol Biochem. 2023. PMID: 37580142
Does Urinary Catheterization Affect the Quality of Death in Patients with Advanced Cancer? A Secondary Analysis of a Multicenter Prospective Cohort Study.
Higashibata T, Hamano J, Hisanaga T, Hagiwara S, Shimokawa M, Yabuki R, Yokomichi N, Shimoinaba J, Kamura R, Baba M, Funaki H, Mori M, Morita T, Tsuneto S, Kizawa Y; East-Asian collaborative cross-cultural Study to Elucidate the Dying Process (EASED) Investigators. Higashibata T, et al. J Palliat Med. 2022 Feb;25(2):205-212. doi: 10.1089/jpm.2021.0178. Epub 2021 Oct 11. J Palliat Med. 2022. PMID: 34637627
Tapentadol Safety and Patient Characteristics Associated with Treatment Discontinuation in Cancer Therapy: A Retrospective Multicentre Study in Japan.
Iwaki M, Kessoku T, Kanamori T, Abe K, Takeno N, Kawahara R, Fujimoto T, Igarashi T, Kumakura Y, Suzuki N, Kamiya K, Suzuki N, Tagami K, Saeki T, Mawatari H, Sakurai H, Higashibata T, Hirohashi T, Nakajima A, Ichikawa Y, Ishiki H; Palliative-Care Investigators’ Network in Kanto (PINK). Iwaki M, et al. Among authors: hirohashi t. Pain Ther. 2021 Dec;10(2):1635-1648. doi: 10.1007/s40122-021-00327-z. Epub 2021 Sep 28. Pain Ther. 2021. PMID: 34581982 Free PMC article.
79 results