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Page 1
Synthesis and evaluation of CS-2100, a potent, orally active and S1P(3)- sparing S1P(1) agonist.
Nakamura T, Asano M, Sekiguchi Y, Mizuno Y, Tamaki K, Nara F, Kawase Y, Yabe Y, Nakai D, Kamiyama E, Urasaki-Kaneno Y, Shimozato T, Doi-Komuro H, Kagari T, Tomisato W, Inoue R, Nagasaki M, Yuita H, Oguchi-Oshima K, Kaneko R, Nishi T. Nakamura T, et al. Among authors: yuita h. Eur J Med Chem. 2012 May;51:92-8. doi: 10.1016/j.ejmech.2012.02.022. Epub 2012 Feb 25. Eur J Med Chem. 2012. PMID: 22405291
Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist.
Nakamura T, Asano M, Sekiguchi Y, Mizuno Y, Tamaki K, Kimura T, Nara F, Kawase Y, Shimozato T, Doi H, Kagari T, Tomisato W, Inoue R, Nagasaki M, Yuita H, Oguchi-Oshima K, Kaneko R, Watanabe N, Abe Y, Nishi T. Nakamura T, et al. Among authors: yuita h. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1788-92. doi: 10.1016/j.bmcl.2011.12.019. Epub 2012 Jan 2. Bioorg Med Chem Lett. 2012. PMID: 22264485
Synthesis and SAR of 1,3-thiazolyl thiophene and pyridine derivatives as potent, orally active and S1P₃-sparing S1P₁ agonists.
Asano M, Nakamura T, Sekiguchi Y, Mizuno Y, Yamaguchi T, Tamaki K, Shimozato T, Doi-Komuro H, Kagari T, Tomisato W, Inoue R, Yuita H, Oguchi-Oshima K, Kaneko R, Nara F, Kawase Y, Masubuchi N, Nakayama S, Koga T, Namba E, Nasu H, Nishi T. Asano M, et al. Among authors: yuita h. Bioorg Med Chem Lett. 2012 May 1;22(9):3083-8. doi: 10.1016/j.bmcl.2012.03.067. Epub 2012 Mar 23. Bioorg Med Chem Lett. 2012. PMID: 22487179
Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist.
Nishi T, Miyazaki S, Takemoto T, Suzuki K, Iio Y, Nakajima K, Ohnuki T, Kawase Y, Nara F, Inaba S, Izumi T, Yuita H, Oshima K, Doi H, Inoue R, Tomisato W, Kagari T, Shimozato T. Nishi T, et al. Among authors: yuita h. ACS Med Chem Lett. 2011 Mar 2;2(5):368-72. doi: 10.1021/ml100301k. eCollection 2011 May 12. ACS Med Chem Lett. 2011. PMID: 24900318 Free PMC article.
Evaluation of species difference in peripheral lymphocyte reduction effect of CS-0777, a sphingosine 1-phosphate receptor modulator, based on a pharmacokinetic/pharmacodynamic model analysis.
Inaba SI, Goto M, Tanaka-Takanaka K, Tanaka H, Tomisato W, Yuita H, Doi-Komuro H, Inoue R, Oshima K, Kagari T, Shimozato T, Izumi T. Inaba SI, et al. Among authors: yuita h. Biopharm Drug Dispos. 2016 Dec;37(9):561-573. doi: 10.1002/bdd.2048. Epub 2016 Nov 14. Biopharm Drug Dispos. 2016. PMID: 27764535
Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals.
Fukuchi K, Nanai K, Yuita H, Maru C, Tsukada J, Ishigami M, Nagai Y, Nakano Y, Yoshimura C, Yoneda K, Amano M, Nakamura K, Oda Y, Nishigohri H, Yamamoto S, Ohnishi-Totoki Y, Inaki K, Komori H, Nakano R, Kanari Y, Nishida A, Matsui Y, Funo S, Takahashi S, Ohtsuka T, Agatsuma T. Fukuchi K, et al. Among authors: yuita h. J Oncol. 2022 Nov 4;2022:3552793. doi: 10.1155/2022/3552793. eCollection 2022. J Oncol. 2022. PMID: 36385956 Free PMC article.
11 results