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Page 1
Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent.
Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: arimura a. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2898-901. doi: 10.1016/j.bmcl.2012.02.050. Epub 2012 Feb 23. Bioorg Med Chem Lett. 2012. PMID: 22421019
CB 1/2 dual agonists with 3-carbamoyl 2-pyridone derivatives as antipruritics: reduction of CNS side effects by introducing polar functional groups.
Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: arimura a. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2894-7. doi: 10.1016/j.bmcl.2012.02.054. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22437111
Discovery of S-777469: an orally available CB2 agonist as an antipruritic agent.
Odan M, Ishizuka N, Hiramatsu Y, Inagaki M, Hashizume H, Fujii Y, Mitsumori S, Morioka Y, Soga M, Deguchi M, Yasui K, Arimura A. Odan M, et al. Among authors: arimura a. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2803-6. doi: 10.1016/j.bmcl.2012.02.072. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22444677
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 1. Bicyclo[2.2.1]heptane derivatives.
Mitsumori S, Tsuri T, Honma T, Hiramatsu Y, Okada T, Hashizume H, Inagaki M, Arimura A, Yasui K, Asanuma F, Kishino J, Ohtani M. Mitsumori S, et al. Among authors: arimura a. J Med Chem. 2003 Jun 5;46(12):2436-45. doi: 10.1021/jm020517g. J Med Chem. 2003. PMID: 12773047
Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives.
Mitsumori S, Tsuri T, Honma T, Hiramatsu Y, Okada T, Hashizume H, Kida S, Inagaki M, Arimura A, Yasui K, Asanuma F, Kishino J, Ohtani M. Mitsumori S, et al. Among authors: arimura a. J Med Chem. 2003 Jun 5;46(12):2446-55. doi: 10.1021/jm0205189. J Med Chem. 2003. PMID: 12773048
Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
Inagaki M, Tsuri T, Jyoyama H, Ono T, Yamada K, Kobayashi M, Hori Y, Arimura A, Yasui K, Ohno K, Kakudo S, Koizumi K, Suzuki R, Kawai S, Kato M, Matsumoto S. Inagaki M, et al. Among authors: arimura a. J Med Chem. 2000 May 18;43(10):2040-8. doi: 10.1021/jm9906015. J Med Chem. 2000. PMID: 10821716
647 results