Déprez B - Search Results

1

Tuberculosis: the drug development pipeline at a glance.

Villemagne B, Crauste C, Flipo M, Baulard AR, Déprez B, Willand N. Villemagne B, et al. Among authors: deprez b. Eur J Med Chem. 2012 May;51:1-16. doi: 10.1016/j.ejmech.2012.02.033. Epub 2012 Feb 25. Eur J Med Chem. 2012. PMID: 22421275 Review.

2

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.

Flipo M, Beghyn T, Charton J, Leroux VA, Deprez BP, Deprez-Poulain RF. Flipo M, et al. Bioorg Med Chem. 2007 Jan 1;15(1):63-76. doi: 10.1016/j.bmc.2006.10.010. Epub 2006 Oct 12. Bioorg Med Chem. 2007. PMID: 17070058

3

Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.

Flipo M, Beghyn T, Leroux V, Florent I, Deprez BP, Deprez-Poulain RF. Flipo M, et al. J Med Chem. 2007 Mar 22;50(6):1322-34. doi: 10.1021/jm061169b. Epub 2007 Feb 28. J Med Chem. 2007. PMID: 17326615

4

Natural compounds: leads or ideas? Bioinspired molecules for drug discovery.

Beghyn T, Deprez-Poulain R, Willand N, Folleas B, Deprez B. Beghyn T, et al. Among authors: deprez poulain r, deprez b. Chem Biol Drug Des. 2008 Jul;72(1):3-15. doi: 10.1111/j.1747-0285.2008.00673.x. Epub 2008 Jun 11. Chem Biol Drug Des. 2008. PMID: 18554253

5

Synthetic EthR inhibitors boost antituberculous activity of ethionamide.

Willand N, Dirié B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Déprez-Poulain R, Delcroix G, Frénois F, Aumercier M, Locht C, Villeret V, Déprez B, Baulard AR. Willand N, et al. Among authors: deprez poulain r, deprez b. Nat Med. 2009 May;15(5):537-44. doi: 10.1038/nm.1950. Epub 2009 May 3. Nat Med. 2009. PMID: 19412174

6

Hydroxamates: relationships between structure and plasma stability.

Flipo M, Charton J, Hocine A, Dassonneville S, Deprez B, Deprez-Poulain R. Flipo M, et al. Among authors: deprez poulain r, deprez b. J Med Chem. 2009 Nov 12;52(21):6790-802. doi: 10.1021/jm900648x. J Med Chem. 2009. PMID: 19821586

7

Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator.

Willand N, Desroses M, Toto P, Dirié B, Lens Z, Villeret V, Rucktooa P, Locht C, Baulard A, Deprez B. Willand N, et al. Among authors: deprez b. ACS Chem Biol. 2010 Nov 19;5(11):1007-13. doi: 10.1021/cb100177g. ACS Chem Biol. 2010. PMID: 20704273

8

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors.

Flipo M, Desroses M, Lecat-Guillet N, Dirié B, Carette X, Leroux F, Piveteau C, Demirkaya F, Lens Z, Rucktooa P, Villeret V, Christophe T, Jeon HK, Locht C, Brodin P, Déprez B, Baulard AR, Willand N. Flipo M, et al. Among authors: deprez b. J Med Chem. 2011 Apr 28;54(8):2994-3010. doi: 10.1021/jm200076a. Epub 2011 Apr 1. J Med Chem. 2011. PMID: 21417236

9

Drug to genome to drug: discovery of new antiplasmodial compounds.

Beghyn TB, Charton J, Leroux F, Laconde G, Bourin A, Cos P, Maes L, Deprez B. Beghyn TB, et al. Among authors: deprez b. J Med Chem. 2011 May 12;54(9):3222-40. doi: 10.1021/jm1014617. Epub 2011 Apr 19. J Med Chem. 2011. PMID: 21504142

10

MALDI imaging techniques dedicated to drug-distribution studies.

Bonnel D, Legouffe R, Willand N, Baulard A, Hamm G, Deprez B, Stauber J. Bonnel D, et al. Among authors: deprez b. Bioanalysis. 2011 Jun;3(12):1399-406. doi: 10.4155/bio.11.88. Bioanalysis. 2011. PMID: 21679033

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