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LYP inhibits T-cell activation when dissociated from CSK.
Vang T, Liu WH, Delacroix L, Wu S, Vasile S, Dahl R, Yang L, Musumeci L, Francis D, Landskron J, Tasken K, Tremblay ML, Lie BA, Page R, Mustelin T, Rahmouni S, Rickert RC, Tautz L. Vang T, et al. Among authors: tremblay ml. Nat Chem Biol. 2012 Mar 18;8(5):437-46. doi: 10.1038/nchembio.916. Nat Chem Biol. 2012. PMID: 22426112 Free PMC article.
Phosphatases in cell-matrix adhesion and migration.
Larsen M, Tremblay ML, Yamada KM. Larsen M, et al. Among authors: tremblay ml. Nat Rev Mol Cell Biol. 2003 Sep;4(9):700-11. doi: 10.1038/nrm1199. Nat Rev Mol Cell Biol. 2003. PMID: 14506473 Review.
Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene.
Spalinger MR, Sanati G, Chatterjee P, Hai R, Li J, Santos AN, Nordgren TM, Tremblay ML, Eckmann L, Hanson E, Scharl M, Wu X, Boland BS, McCole DF. Spalinger MR, et al. Among authors: tremblay ml. Cell Mol Gastroenterol Hepatol. 2025 Jan 3:101447. doi: 10.1016/j.jcmgh.2024.101447. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2025. PMID: 39756517 Free article.
Osteopontin is a therapeutic target that drives breast cancer recurrence.
Gu Y, Taifour T, Bui T, Zuo D, Pacis A, Poirier A, Attalla S, Fortier AM, Sanguin-Gendreau V, Pan TC, Papavasiliou V, Lin NU, Hughes ME, Smith K, Park M, Tremblay ML, Chodosh LA, Jeselsohn R, Muller WJ. Gu Y, et al. Among authors: tremblay ml. Nat Commun. 2024 Oct 24;15(1):9174. doi: 10.1038/s41467-024-53023-9. Nat Commun. 2024. PMID: 39448577 Free PMC article.
PTPRS is a novel marker for early tau pathology and synaptic integrity in Alzheimer's disease.
Poirier A, Picard C, Labonté A, Aubry I, Auld D, Zetterberg H, Blennow K; PREVENT-AD research group; Tremblay ML, Poirier J. Poirier A, et al. Among authors: tremblay ml. bioRxiv [Preprint]. 2024 May 12:2024.05.12.593733. doi: 10.1101/2024.05.12.593733. bioRxiv. 2024. Update in: Sci Rep. 2024 Jun 26;14(1):14718. doi: 10.1038/s41598-024-65104-2 PMID: 38766183 Free PMC article. Updated. Preprint.
252 results