Grogan JL - Search Results

1

In vivo depletion of lymphotoxin-alpha expressing lymphocytes inhibits xenogeneic graft-versus-host-disease.

Chiang EY, Kolumam G, McCutcheon KM, Young J, Lin Z, Balazs M, Grogan JL. Chiang EY, et al. Among authors: grogan jl. PLoS One. 2012;7(3):e33106. doi: 10.1371/journal.pone.0033106. Epub 2012 Mar 12. PLoS One. 2012. PMID: 22427961 Free PMC article.

2

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Yu X, Harden K, Gonzalez LC, Francesco M, Chiang E, Irving B, Tom I, Ivelja S, Refino CJ, Clark H, Eaton D, Grogan JL. Yu X, et al. Among authors: grogan jl. Nat Immunol. 2009 Jan;10(1):48-57. doi: 10.1038/ni.1674. Epub 2008 Nov 16. Nat Immunol. 2009. PMID: 19011627

3

Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease.

Chiang EY, Kolumam GA, Yu X, Francesco M, Ivelja S, Peng I, Gribling P, Shu J, Lee WP, Refino CJ, Balazs M, Paler-Martinez A, Nguyen A, Young J, Barck KH, Carano RA, Ferrando R, Diehl L, Chatterjea D, Grogan JL. Chiang EY, et al. Among authors: grogan jl. Nat Med. 2009 Jul;15(7):766-73. doi: 10.1038/nm.1984. Epub 2009 Jun 28. Nat Med. 2009. PMID: 19561618

4

Lymphotoxin-alphabeta heterotrimers are cleaved by metalloproteinases and contribute to synovitis in rheumatoid arthritis.

Young J, Yu X, Wolslegel K, Nguyen A, Kung C, Chiang E, Kolumam G, Wei N, Wong WL, DeForge L, Townsend MJ, Grogan JL. Young J, et al. Among authors: grogan jl. Cytokine. 2010 Jul;51(1):78-86. doi: 10.1016/j.cyto.2010.03.003. Epub 2010 Mar 31. Cytokine. 2010. PMID: 20356761

5

Immune complex-mediated cell activation from systemic lupus erythematosus and rheumatoid arthritis patients elaborate different requirements for IRAK1/4 kinase activity across human cell types.

Chiang EY, Yu X, Grogan JL. Chiang EY, et al. Among authors: grogan jl. J Immunol. 2011 Jan 15;186(2):1279-88. doi: 10.4049/jimmunol.1002821. Epub 2010 Dec 15. J Immunol. 2011. PMID: 21160042

6

Resurrection of a clinical antibody: template proteogenomic de novo proteomic sequencing and reverse engineering of an anti-lymphotoxin-α antibody.

Castellana NE, McCutcheon K, Pham VC, Harden K, Nguyen A, Young J, Adams C, Schroeder K, Arnott D, Bafna V, Grogan JL, Lill JR. Castellana NE, et al. Among authors: grogan jl. Proteomics. 2011 Feb;11(3):395-405. doi: 10.1002/pmic.201000487. Epub 2011 Jan 5. Proteomics. 2011. PMID: 21268269 Free PMC article.

7

Safety, pharmacokinetics, and biologic activity of pateclizumab, a novel monoclonal antibody targeting lymphotoxin α: results of a phase I randomized, placebo-controlled trial.

Emu B, Luca D, Offutt C, Grogan JL, Rojkovich B, Williams MB, Tang MT, Xiao J, Lee JH, Davis JC. Emu B, et al. Among authors: grogan jl. Arthritis Res Ther. 2012 Jan 8;14(1):R6. doi: 10.1186/ar3554. Arthritis Res Ther. 2012. PMID: 22225620 Free PMC article. Clinical Trial.

8

Controlling herpetic stromal keratitis by modulating lymphotoxin-alpha-mediated inflammatory pathways.

Veiga-Parga T, Giménez F, Mulik S, Chiang EY, Grogan JL, Rouse BT. Veiga-Parga T, et al. Among authors: grogan jl. Microbes Infect. 2013 Sep-Oct;15(10-11):677-87. doi: 10.1016/j.micinf.2013.07.001. Epub 2013 Jul 10. Microbes Infect. 2013. PMID: 23850656 Free PMC article.

9

Dimerization of LTβR by LTα1β2 is necessary and sufficient for signal transduction.

Sudhamsu J, Yin J, Chiang EY, Starovasnik MA, Grogan JL, Hymowitz SG. Sudhamsu J, et al. Among authors: grogan jl. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19896-901. doi: 10.1073/pnas.1310838110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248355 Free PMC article.

10

EBI2 is a negative regulator of type I interferons in plasmacytoid and myeloid dendritic cells.

Chiang EY, Johnston RJ, Grogan JL. Chiang EY, et al. Among authors: grogan jl. PLoS One. 2013 Dec 26;8(12):e83457. doi: 10.1371/journal.pone.0083457. eCollection 2013. PLoS One. 2013. PMID: 24386204 Free PMC article.

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